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TRIM21 抗体 (N-Term)

This anti-TRIM21 antibody is a 兔 多克隆 antibody detecting TRIM21 in WB. Suitable for 人, 小鼠, 大鼠, 豚鼠, 犬 和 兔.
产品编号 ABIN2778305
发货至: 中国

Quick Overview for TRIM21 抗体 (N-Term) (ABIN2778305)

抗原

See all TRIM21 抗体
TRIM21 (Tripartite Motif Containing 21 (TRIM21))

适用

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人, 小鼠, 大鼠, 豚鼠, 犬, 兔

宿主

  • 61
  • 8
  • 2
  • 1
  • 1

克隆类型

  • 66
  • 7
多克隆

标记

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This TRIM21 antibody is un-conjugated

应用范围

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  • 3
  • 2
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  • 1
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Western Blotting (WB)
  • 抗原表位

    • 15
    • 11
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
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    • 1
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    N-Term

    序列

    GELRRKQELA EKLEVEIAIK RADWKKTVET QKSRIHAEFV QQKNFLVEEE

    预测反应

    Dog: 77%, Guinea Pig: 92%, Human: 100%, Mouse: 83%, Rabbit: 85%, Rat: 85%

    产品特性

    This is a rabbit polyclonal antibody against TRIM21. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human TRIM21
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 475 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    TRIM21 (Tripartite Motif Containing 21 (TRIM21))

    别名

    TRIM21

    背景

    TRIM21 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. TRIM21 is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus.This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: RNF81, RO52, SSA, SSA1
    Protein Interaction Partner: TRIM39, IGHV4-31, TXN2, GRAP, UBE2I, TRIM21, IGHG1, USP15, HAUS2, UBE2D2, UBC, FBXO6, UBD, NPM1, PAN2, ROR1, NOS2, MYC, IQCB1, USP2, VCP, USP4, CDC34, CBL, UBC4, UBE2C, UBE2L3, UBE2H, UBE2D1, TROVE2, TRIM27, MNAT1, FCGR2A, CD52, DCP2, ZFPM1, TRIM5, TRIM8,
    Protein Size: 475

    分子量

    54 kDa

    基因ID

    6737

    NCBI登录号

    NM_003141, NP_003132

    UniProt

    P19474
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