Atrophin 1 抗体 (N-Term)
Quick Overview for Atrophin 1 抗体 (N-Term) (ABIN2778293)
抗原
See all Atrophin 1 (ATN1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- VSTSSSDGKA EKSRQTAKKA RVEEASTPKV NKQGRSEEIS ESESEETNAP
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预测反应
- Cow: 93%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 100%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against ATN1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human ATN1
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 1190 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Atrophin 1 (ATN1)
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别名
- ATN1
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背景
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Dentatorubral pallidoluysian atrophy is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. The disorder is related to the expansion of a trinucleotide repeat within ATN1. The protein includes a serine repeat and a region of alternating acidic and basic amino acids, as well as the variable glutamine repeat. Alternative splicing results in two transcripts variants that encode the same protein.Dentatorubral pallidoluysian atrophy is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. The disorder is related to the expansion of a trinucleotide repeat within this gene. The encoded protein includes a serine repeat and a region of alternating acidic and basic amino acids, as well as the variable glutamine repeat. Alternative splicing results in two transcripts variants that encode the same protein.
Alias Symbols: B37, D12S755E, DRPLA, NOD, HRS
Protein Interaction Partner: WWOX, Dlg4, SIAH1, HINFP, LRP2, RBFOX1, EFEMP2, NOC2L, RCHY1, ZMYND8, RBFOX2, KAT6B, SSPO, RAD54L2, ZSWIM8, WDR5, WWP2, WWP1, RBPMS, SPAG5, FBLN5, BAIAP2, PSME3, CBFA2T2, CHRD, NCK2, LTBP4, RBM10, KAT6A, BAG6, PRRC2A, TRIP6, TEP1, SLIT1, SIAH2, PSMA3, PLS
Protein Size: 1190 -
分子量
- 125 kDa
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基因ID
- 1822
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NCBI登录号
- NM_001940, NP_001931
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UniProt
- P54259
抗原
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