Tryptophan Hydroxylase 2 抗体 (Middle Region)
(1 reference)-
- 抗原 See all Tryptophan Hydroxylase 2 (TPH2) 抗体
- Tryptophan Hydroxylase 2 (TPH2)
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, 犬, Cow, 马, 豚鼠, 兔, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Tryptophan Hydroxylase 2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- KMRDFAKSIT RPFSVYFNPY TQSIEILKDT RSIENVVQDL RSDLNTVCDA
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- 产品特性
- This is a rabbit polyclonal antibody against TPH2. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human TPH2
- Top Product
- Discover our top product TPH2 Primary Antibody
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anti-Tryptophan Hydroxylase 2 (TPH2) (Internal Region) antibody
Verified TPH2 适用: 人 ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Tryptophan Hydroxylase 2 (TPH2) (AA 44-225) antibodyTPH2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tryptophan Hydroxylase 2 (TPH2) antibodyMicroarray verified TPH2 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB425277 unconjugated
anti-Tryptophan Hydroxylase 2 (TPH2) antibodyTPH2 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tryptophan Hydroxylase 2 (TPH2) antibodyMicroarray verified TPH2 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB822648 unconjugated
anti-Tryptophan Hydroxylase 2 (TPH2) (AA 1-170) antibodyTPH2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Tryptophan Hydroxylase 2 (TPH2) antibodyMicroarray verified TPH2 适用: 人 IHC 宿主: 小鼠 Monoclonal MAB282025 unconjugated
anti-Tryptophan Hydroxylase 2 (TPH2) antibodyMicroarray verified TPH2 适用: 人 IHC 宿主: 小鼠 Monoclonal MAB26484 unconjugated
anti-Tryptophan Hydroxylase 2 (TPH2) (AA 16-29) antibodyVerified TPH2 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Tryptophan Hydroxylase 2 (TPH2) (Internal Region) antibodyVerified TPH2 适用: 小鼠 ELISA, IF 宿主: 山羊 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 490 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Common genetic variations in human brain-specific tryptophan hydroxylase-2 and response to antidepressant treatment." in: Pharmacogenetics and genomics, Vol. 18, Issue 6, pp. 495-506, (2008) (PubMed).
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: "Common genetic variations in human brain-specific tryptophan hydroxylase-2 and response to antidepressant treatment." in: Pharmacogenetics and genomics, Vol. 18, Issue 6, pp. 495-506, (2008) (PubMed).
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- 抗原
- Tryptophan Hydroxylase 2 (TPH2)
- 别名
- TPH2 (TPH2 产品)
- 背景
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Tryptophan hydroxylase (TPH, EC 1.14.16.4) is the rate-limiting enzyme in the synthesis of serotonin (5-hydroxytryptamine, or 5HT). 5HT is causally involved in numerous central nervous activities, and it has several functions in peripheral tissues, including the maintenance of vascular tone and gut motility. This gene encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. The human genome contains two related tryptophan hydroxylases, one on chromosome 11p15-p14 and one on chromosome 12q21. This gene is expressed predominantly in the brain stem. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by the mouse ortholog. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1805 AY098914.1 1-1805 1806-2360 AC090109.15 122981-123535
Alias Symbols: FLJ37295, MGC138871, MGC138872, NTPH, ADHD7
Protein Interaction Partner: UBC,
Protein Size: 490 - 分子量
- 56 kDa
- 基因ID
- 121278
- NCBI登录号
- NM_173353, NP_775489
- UniProt
- Q8IWU9
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