Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1) (N-Term) 抗体

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抗原
  • npm4
  • npm
  • B23
  • NPM
  • NO38
  • B23NP
  • Npm
  • CG7917
  • CRP1
  • Crp1
  • Dmel\\CG7917
  • dNLP
  • dNLP-S
  • p22
  • nucleophosmin 1
  • nucleophosmin 1b
  • Nucleophosmin
  • nucleophosmin (nucleolar phosphoprotein B23, numatrin) L homeolog
  • nucleophosmin
  • nucleophosmin (nucleolar phosphoprotein B23, numatrin)
  • Nucleoplasmin
  • NPM1
  • npm1b
  • npm
  • npm1.L
  • Npm1
  • Nlp
抗原表位
N-Term
48
33
30
27
26
22
18
17
16
10
7
5
5
4
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
适用
牛, 犬, 豚鼠, 马, 人, 小鼠, 猪, 兔, 大鼠
375
182
169
19
19
16
15
14
10
10
5
3
3
2
1
1
1
1
1
1
1
宿主

261
126
19
1
1
克隆类型
多克隆
标记
非结合性
16
12
8
6
6
5
5
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
应用范围
Immunohistochemistry (IHC), Western Blotting (WB)
344
173
171
116
103
48
42
40
27
19
6
5
4
3
选项
Supplier
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免疫原 The immunogen is a synthetic peptide directed towards the N terminal region of human NPM1
序列 DMDMSPLRPQ NYLFGCELKA DKDYHFKVDN DENEHQLSLR TVSLGAGAKD
预测反应 Cow: 93%, Dog: 100%, Guinea Pig: 77%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
产品特性 This is a rabbit polyclonal antibody against NPM1. It was validated on Western Blot and immunohistochemistry.
纯化方法 Protein A purified
抗原 Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1)
别名 NPM1 (NPM1 Antibody 摘要)
背景 NPM1 is a member of Nucleophosmin (NPM) family. NPM is a ubiquitously expressed nucleolar phosphoprotein that continuously shuttles between the nucleus and cytoplasm
Alias Symbols: B23, NPM
Protein Interaction Partner: COX8A, NPM2, HUWE1, UBC, PA2G4, FUS, TP53, AURKA, SUMO2, SUMO3, ELF4, STAU1, CDKN2A, LGR4, SUMO1, MDM2, RPA3, RPA2, RPA1, ERG, rev, TRMT61A, OSBP, KPNA1, LIMCH1, ARMCX3, YWHAQ, PARK2, TARDBP, TUBA1C, TAB2, CEP152, DZIP1, COPG1, STK38, COPE, PARK7, AKAP11,
Protein Size: 294
分子量 33 kDa
基因ID 4869
NCBI登录号 NM_002520, NP_002511
UniProt P06748
途径 Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
应用备注 Optimal working dilutions should be determined experimentally by the investigator.
说明

Antigen size: 294 AA

限制 仅限研究用
状态 Liquid
浓度 Lot specific
缓冲液 Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freeze-thaw cycles.
储存条件 -20 °C
储存方法 For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
厂商提供的图像
Western Blotting (WB) image for anti-Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1) (N-Term) antibody (ABIN2778260) WB Suggested Anti-NPM1 Antibody Titration: 1.0ug/ml Positive Control: HepG2 cell l...
Immunohistochemistry (IHC) image for anti-Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1) (N-Term) antibody (ABIN2778260) Sample Type: human cornea (frozen)
Blue: DAPI
Red: NPM1
Immunohistochemistry (IHC) image for anti-Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1) (N-Term) antibody (ABIN2778260) Human Lung
Western Blotting (WB) image for anti-Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1) (N-Term) antibody (ABIN2778260) Host: Mouse Target Name: NPM1 Sample Tissue: Mouse Spleen Antibody Dilution: 1...
有引用在: Komorek, Kuppuswamy, Subramanian, Vijayalingam, Lomonosova, Zhao, Mymryk, Schmitt, Chinnadurai: "Adenovirus type 5 E1A and E6 proteins of low-risk cutaneous beta-human papillomaviruses suppress cell transformation through interaction with FOXK1/K2 transcription factors." in: Journal of virology, Vol. 84, Issue 6, pp. 2719-31, 2010 (PubMed).

Lin, Coutinho-Mansfield, Wang, Pandit, Fu: "The splicing factor SC35 has an active role in transcriptional elongation." in: Nature structural & molecular biology, Vol. 15, Issue 8, pp. 819-26, 2008 (PubMed).

背景 Falini, Mecucci, Tiacci, Alcalay, Rosati, Pasqualucci, La Starza, Diverio, Colombo, Santucci, Bigerna, Pacini, Pucciarini, Liso, Vignetti, Fazi, Meani, Pettirossi, Saglio, Mandelli, Lo-Coco, Pelicci et al.: "Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype. ..." in: The New England journal of medicine, Vol. 352, Issue 3, pp. 254-66, 2005 (PubMed).

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