RGS20 抗体 (N-Term)
Quick Overview for RGS20 抗体 (N-Term) (ABIN2778241)
抗原
See all RGS20 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- NACCFCWCCC CSCSCLTVRN QEDQRPTIAS HELRADLPTW EESPAPTLEE
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特异性
- 100 % homologous to isoforms 1, 2, 4-6.
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预测反应
- Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 85%, Rat: 79%
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产品特性
- This is a rabbit polyclonal antibody against RGS20. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 241 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- RGS20 (Regulator of G-Protein Signaling 20 (RGS20))
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别名
- RGS20
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背景
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The protein encoded by this gene belongs to the family of regulator of G protein signaling (RGS) proteins, which are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins inhibit signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound forms. This protein selectively binds to G(z)-alpha and G(alpha)-i2 subunits, and regulates their signaling activities. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: RGSZ1, ZGAP1
Protein Interaction Partner: KRTAP5-6, LCE3E, LCE2D, LCE2A, LCE1B, KLHL38, LCE4A, TBC1D16, CATSPER1, PTPMT1, KRTAP4-2, CRCT1, PVRL3, MAPKBP1, GLRX3, CREB5, PTGER3, OTX1, KRTAP5-9, INS, HSPD1, HOXA1, GNAI2, AQP1, FASLG, KIF1A, ADRB2, OSTM1, STMN2, GNAI3, GNAI1, GNAZ, UBC, GNAO1, TXLNA
Protein Size: 241 -
分子量
- 27 kDa
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基因ID
- 8601
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NCBI登录号
- NM_003702, NP_003693
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UniProt
- O76081
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途径
- Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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