KIF2A 抗体 (C-Term)
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北京 101111
Quick Overview for KIF2A 抗体 (C-Term) (ABIN2778232)
抗原
See all KIF2A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- KIF2A Antibody - C-terminal region
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序列
- ETQWGVGSSP QRDDLKLLCE QNEEEVSPQL FTFHEAVSQM VEMEEQVVED
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
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产品特性
- This is a rabbit polyclonal antibody against KIF2A. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human KIF2A
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP34033-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- KIF2A (Kinesin Heavy Chain Member 2A (KIF2A))
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别名
- KIF2A
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背景
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Background Information: KIF2A belongs to the kinesin-like protein family, MCAK/KIF2 subfamily. It contains 1 kinesin-motor domain. KIF2A plus end-directed microtubule-dependent motor required for normal brain development. It may regulate microtubule dynamics during axonal growth. KIF2A is implicated in formation of bipolar mitotic spindles. It has microtubule depolymerization activity. Hela cells lacking KIF2A show asymmetric or monopolar mitotic spindles. Osteosarcoma cells (U2OS) lacking KIF2A or KIF2B show disorganised or monopolar mitotic spindles.Kinesins, such as KIF2, are microtubule-associated motor proteins. For background information on kinesins, see MIM 148760.[supplied by OMIM].
Gene Name: Kinesin heavy chain member 2A
Alternative Symbols: HK2, KIF2, CDCBM3
Protein Name: Kinesin-like protein KIF2A
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分子量
- 80kDa
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基因ID
- 3796
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NCBI登录号
- NP_004511
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UniProt
- O00139
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途径
- Microtubule Dynamics, Ribonucleoprotein Complex Subunit Organization
抗原
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