NCOA1 抗体 (Middle Region)
Quick Overview for NCOA1 抗体 (Middle Region) (ABIN2778219)
抗原
See all NCOA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- GLLHNNDRLS DGDSKYSQTS HKLVQLLTTT AEQQLRHADI DTSCKDVLSC
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预测反应
- Cow: 93%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against NCOA1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human NCOA1
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anti-Nuclear Receptor Coactivator 1 (NCOA1) (AA 1222-1441) antibody
NCOA1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Coactivator 1 (NCOA1) antibodyNCOA1 适用: 人 WB, IP 宿主: 兔 Monoclonal unconjugated
anti-Nuclear Receptor Coactivator 1 (NCOA1) (pTyr529) antibodyNCOA1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Coactivator 1 (NCOA1) (AA 1338-1367) antibodyNCOA1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Coactivator 1 (NCOA1) (AA 201-300) antibodyNCOA1 适用: 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Coactivator 1 (NCOA1) (AA 284-393) antibodyNCOA1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Coactivator 1 (NCOA1) (N-Term) antibodyNCOA1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Coactivator 1 (NCOA1) antibodyNCOA1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Coactivator 1 (NCOA1) (AA 611-660) antibodyNCOA1 适用: 人, 大鼠, 犬, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Coactivator 1 (NCOA1) antibodyNCOA1 适用: 人 DB 宿主: 小鼠 Monoclonal 3532C6a unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 1399 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- NCOA1 (Nuclear Receptor Coactivator 1 (NCOA1))
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别名
- NCOA1
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背景
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NCOA1 acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. NCOA1 binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion.The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: F-SRC-1, KAT13A, MGC129719, MGC129720, NCoA-1, RIP160, SRC1, bHLHe42, bHLHe74
Protein Interaction Partner: ASCC1, NR1I2, PPARG, AR, VDR, THRB, RXRA, RORB, RORA, RARA, HNF4G, NR6A1, NR5A2, ESRRA, ESR1, PAGR1, Esr2, NR3C1, CXADR, PPARA, AHR, KANK2, NCOA2, TRIM24, NCOA1, ANIB1, PGR, COPS5, UBE2L3, TP53, NCOA6, EP300, UBC, RARB, PPARD, RARG, RBBP6, CREBBP, STAT3,
Protein Size: 1399 -
分子量
- 152 kDa
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基因ID
- 8648
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NCBI登录号
- NM_147223, NP_671756
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
抗原
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