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Cholesterol Esterase 抗体 (C-Term)

CEL 适用: 人, 小鼠, 大鼠, 马, Pig WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2778160
发货至: 中国
  • 抗原 See all Cholesterol Esterase (CEL) 抗体
    Cholesterol Esterase (CEL)
    抗原表位
    • 7
    • 6
    • 6
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 36
    • 12
    • 6
    • 4
    • 3
    • 2
    人, 小鼠, 大鼠, 马, Pig
    宿主
    • 41
    • 4
    克隆类型
    • 41
    • 4
    多克隆
    标记
    • 18
    • 8
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Cholesterol Esterase antibody is un-conjugated
    应用范围
    • 30
    • 29
    • 10
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    VTPTGDSETA PVPPTGDSGA PPVPPTGDSE AAPVPPTDDS KEAQMPAVIR
    预测反应
    Horse: 77%, Human: 100%, Mouse: 77%, Pig: 85%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against CEL. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C - terminal region of human CEL
    Top Product
    Discover our top product CEL Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 756 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Panicot-Dubois, Thomas, Furie, Furie, Lombardo, Dubois: "Bile salt-dependent lipase interacts with platelet CXCR4 and modulates thrombus formation in mice and humans." in: The Journal of clinical investigation, Vol. 117, Issue 12, pp. 3708-19, (2007) (PubMed).

  • 抗原
    Cholesterol Esterase (CEL)
    别名
    CEL (CEL 产品)
    别名
    SC8F4.24 antibody, BAL antibody, BSDL antibody, BSSL antibody, CELL antibody, CEase antibody, FAP antibody, FAPP antibody, LIPA antibody, MODY8 antibody, 1810036E18Rik antibody, Bal antibody, Bssl antibody, carboxyl ester lipase antibody, cholesterol esterase antibody, hypothetical protein antibody, CEL antibody, SCO5420 antibody, Tfu_2331 antibody, SARE_RS01070 antibody, RSal33209_1252 antibody, Caci_5976 antibody, Ndas_0054 antibody, Micau_5972 antibody, ML5_2523 antibody, Cel antibody, cel antibody
    背景
    CEL catalyzes fat and vitamin absorption. CEL acts in concert with pancreatic lipase and colipase for the complete digestion of dietary triglycerides.The protein encoded by this gene is a glycoprotein secreted from the pancreas into the digestive tract and from the lactating mammary gland into human milk. The physiological role of this protein is in cholesterol and lipid-soluble vitamin ester hydrolysis and absorption. This encoded protein promotes large chylomicron production in the intestine. Also its presence in plasma suggests its interactions with cholesterol and oxidized lipoproteins to modulate the progression of atherosclerosis. In pancreatic tumoral cells, this encoded protein is thought to be sequestrated within the Golgi compartment and is probably not secreted. This gene contains a variable number of tandem repeat (VNTR) polymorphism in the coding region that may influence the function of the encoded protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: BAL, BSDL, BSSL, CELL, CEase, FAP, FAPP, LIPA, MODY8
    Protein Interaction Partner: OLR1, BPGM, LTF,
    Protein Size: 756
    分子量
    80 kDa
    基因ID
    1056
    NCBI登录号
    NM_001807, NP_001798
    UniProt
    P19835
    途径
    Lipid Metabolism
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