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Cholesterol Esterase 抗体 (C-Term)

This anti-Cholesterol Esterase antibody is a 兔 多克隆 antibody detecting Cholesterol Esterase in WB. Suitable for 人, 小鼠, 大鼠, 马 和 Pig. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2778160
发货至: 中国

Quick Overview for Cholesterol Esterase 抗体 (C-Term) (ABIN2778160)

抗原

See all Cholesterol Esterase (CEL) 抗体
Cholesterol Esterase (CEL)

适用

  • 35
  • 12
  • 4
  • 4
  • 2
  • 1
人, 小鼠, 大鼠, 马, Pig

宿主

  • 37
  • 3

克隆类型

  • 37
  • 3
多克隆

标记

  • 21
  • 5
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Cholesterol Esterase antibody is un-conjugated

应用范围

  • 27
  • 21
  • 9
  • 5
  • 5
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 6
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    序列

    VTPTGDSETA PVPPTGDSGA PPVPPTGDSE AAPVPPTDDS KEAQMPAVIR

    预测反应

    Horse: 77%, Human: 100%, Mouse: 77%, Pig: 85%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against CEL. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C - terminal region of human CEL
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 756 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Panicot-Dubois, Thomas, Furie, Furie, Lombardo, Dubois: "Bile salt-dependent lipase interacts with platelet CXCR4 and modulates thrombus formation in mice and humans." in: The Journal of clinical investigation, Vol. 117, Issue 12, pp. 3708-19, (2007) (PubMed).

  • 抗原

    Cholesterol Esterase (CEL)

    别名

    CEL

    背景

    CEL catalyzes fat and vitamin absorption. CEL acts in concert with pancreatic lipase and colipase for the complete digestion of dietary triglycerides.The protein encoded by this gene is a glycoprotein secreted from the pancreas into the digestive tract and from the lactating mammary gland into human milk. The physiological role of this protein is in cholesterol and lipid-soluble vitamin ester hydrolysis and absorption. This encoded protein promotes large chylomicron production in the intestine. Also its presence in plasma suggests its interactions with cholesterol and oxidized lipoproteins to modulate the progression of atherosclerosis. In pancreatic tumoral cells, this encoded protein is thought to be sequestrated within the Golgi compartment and is probably not secreted. This gene contains a variable number of tandem repeat (VNTR) polymorphism in the coding region that may influence the function of the encoded protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: BAL, BSDL, BSSL, CELL, CEase, FAP, FAPP, LIPA, MODY8
    Protein Interaction Partner: OLR1, BPGM, LTF,
    Protein Size: 756

    分子量

    80 kDa

    基因ID

    1056

    NCBI登录号

    NM_001807, NP_001798

    UniProt

    P19835

    途径

    Lipid Metabolism
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