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PLP1 抗体 (Middle Region)

The 兔 多克隆 anti-PLP1 antibody (ABIN2778152) specifically detects PLP1 in WB 和 IHC. The antibody is reactive with 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马 和 兔 samples.
产品编号 ABIN2778152
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PLP1 抗体 (Middle Region) (ABIN2778152)

抗原

See all PLP1 抗体
PLP1 (Proteolipid Protein 1 (PLP1))

适用

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人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔

宿主

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兔

克隆类型

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多克隆

标记

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This PLP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    Middle Region

    原理

    PLP1 Antibody - middle region

    序列

    IYGTASFFFL YGALLLAEGF YTTGAVRQIF GDYKTTICGK GLSATVTGGQ

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against PLP1. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human PLP1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8109549

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    PLP1 (Proteolipid Protein 1 (PLP1))

    别名

    PLP1

    背景

    Background Information: PLP1 is a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system. It may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2.This gene encodes a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system. It may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively spliced transcript variants encoding distinct isoforms or having different 5' UTRs, have been identified for this gene.

    Gene Name: Proteolipid protein 1

    Alternative Symbols: PLP, PMD, HLD1, MMPL, SPG2, GPM6C, PLP/DM20

    Protein Name: Myelin proteolipid protein

    分子量

    30kDa

    基因ID

    5354

    NCBI登录号

    NP_000524

    UniProt

    P60201
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