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PLP1 抗体 (N-Term)

This 兔 多克隆 anti-PLP1 antibody specifically detects PLP1 in WB 和 IHC. The antibody is reactive with 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 兔 和 斑马鱼 samples.
产品编号 ABIN2778151
发货至: 中国
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Quick Overview for PLP1 抗体 (N-Term) (ABIN2778151)

抗原

See all PLP1 抗体
PLP1 (Proteolipid Protein 1 (PLP1))

适用

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人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼

宿主

  • 36
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克隆类型

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多克隆

标记

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This PLP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 16
    • 4
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    N-Term

    序列

    GHEALTGTEK LIETYFSKNY QDYEYLINVI HAFQYVIYGT ASFFFLYGAL

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 75%

    产品特性

    This is a rabbit polyclonal antibody against PLP1. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human PLP1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 277 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    PLP1 (Proteolipid Protein 1 (PLP1))

    别名

    PLP1

    背景

    PLP1 is a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system. It may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively spliced transcript variants encoding distinct isoforms or having different 5' UTRs, have been identified for this gene.This gene encodes a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system. It may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively spliced transcript variants encoding distinct isoforms or having different 5' UTRs, have been identified for this gene.
    Alias Symbols: MMPL, PLP, PLP/DM20, PMD, SPG2, HLD1
    Protein Interaction Partner: PTPRN, CLN8, Htt, ITGAV, ITGA5, MAG, MBP, CANX, CALR,
    Protein Size: 277

    分子量

    30 kDa

    基因ID

    5354

    NCBI登录号

    NM_000533, NP_000524

    UniProt

    P60201
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