PARP11 抗体 (Middle Region)
Quick Overview for PARP11 抗体 (Middle Region) (ABIN2778116)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- IKHGNTFQIH GVSLQQRHLF RTYKSMFLAR VLIGDYINGD SKYMRPPSKD
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预测反应
- Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against PARP11. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human PARP11
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anti-Poly (ADP-Ribose) Polymerase Family, Member 11 (PARP11) antibody
PARP11 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase Family, Member 11 (PARP11) (N-Term) antibodyPARP11 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 豚鼠, 兔, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase Family, Member 11 (PARP11) (AA 252-301) antibodyPARP11 适用: 人, 小鼠, 大鼠, 豚鼠, 兔, Pig, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase Family, Member 11 (PARP11) (AA 112-161) antibodyPARP11 适用: 人, 大鼠, Cow, 犬, 马, Bat WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 331 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PARP11 (Poly (ADP-Ribose) Polymerase Family, Member 11 (PARP11))
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别名
- PARP11
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背景
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PARP1 encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. PARP1 can be cleaved resulting in fragements of 29 and 85 kDa.
Alias Symbols: C12orf6, DKFZp779H0122
Protein Interaction Partner: MDFI, TRIP13, DCAF11, RNF114, OTUD4, LYZ, GTPBP3, NUP98,
Protein Size: 331 -
分子量
- 39 kDa
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基因ID
- 57097
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NCBI登录号
- NM_020367, NP_065100
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UniProt
- Q9NR21
抗原
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