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Tiparp 抗体 (N-Term)

There are 2+ publications for this product available. The 兔 多克隆 anti-Tiparp antibody is suitable to detect Tiparp in samples from 人, 小鼠, 大鼠, Cow, 犬, 马, Pig 和 兔. It has been validated for WB.
产品编号 ABIN404897
发货至: 中国
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Quick Overview for Tiparp 抗体 (N-Term) (ABIN404897)

抗原

See all Tiparp 抗体
Tiparp (TCDD-Inducible Poly(ADP-Ribose) Polymerase (Tiparp))

适用

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人, 小鼠, 大鼠, Cow, 犬, 马, Pig, 兔

宿主

  • 21

克隆类型

  • 21
多克隆

标记

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This Tiparp antibody is un-conjugated

应用范围

  • 9
  • 6
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Western Blotting (WB)
  • 抗原表位

    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    N-Term

    序列

    LKTCFKKKDQ KRLGTGTLRS LRPILNTLLE SGSLDGVFRS RNQSTDENSL

    预测反应

    Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 83%, Pig: 100%, Rabbit: 92%, Rat: 83%

    产品特性

    This is a rabbit polyclonal antibody against TIPARP. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human TIPARP
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 657 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • MacPherson, Tamblyn, Rajendra, Bralha, McPherson, Matthews: "2,3,7,8-Tetrachlorodibenzo-p-dioxin poly(ADP-ribose) polymerase (TiPARP, ARTD14) is a mono-ADP-ribosyltransferase and repressor of aryl hydrocarbon receptor transactivation." in: Nucleic acids research, Vol. 41, Issue 3, pp. 1604-21, (2013) (PubMed).

    Mehrle, Rosenfelder, Schupp, del Val, Arlt, Hahne, Bechtel, Simpson, Hofmann, Hide, Glatting, Huber, Pepperkok, Poustka, Wiemann: "The LIFEdb database in 2006." in: Nucleic acids research, Vol. 34, Issue Database issue, pp. D415-8, (2005) (PubMed).

  • 抗原

    Tiparp (TCDD-Inducible Poly(ADP-Ribose) Polymerase (Tiparp))

    别名

    TIPARP

    背景

    TIPARP is a poly [ADP-ribose] polymerase using NAD+ as a substrate to transfer ADP-ribose onto glutamic acid residues of a protein acceptor, repeated rounds of ADP-ribosylation leads to the formation of poly(ADPribose) chains on the protein, thereby altering the function of the target protein. TIPARP may play a role in the adaptative response to chemical exposure (TCDD) and thereby mediates certain effects of the chemicals.
    Alias Symbols: DDF1, DKFZP434J214, DKFZp686N0351, DKFZp686P1838, FLJ40466, PARP-1, PARP-7, PARP7, pART14
    Protein Interaction Partner: UBC, XRN2, ATM,
    Protein Size: 657

    分子量

    76 kDa

    基因ID

    25976

    NCBI登录号

    NM_015508, NP_056323

    UniProt

    Q7Z3E1

    途径

    Platelet-derived growth Factor Receptor Signaling
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