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PARP3 抗体 (C-Term)

This anti-PARP3 antibody (ABIN2778113) is a Rabbit Polyclonal antibody detecting PARP3 in WB, IHC. Suitable for Human, Mouse, Rat, Horse, Rabbit, Cow, Dog, Pig.
产品编号 ABIN2778113
发货至: 中国

Quick Overview for PARP3 抗体 (C-Term) (ABIN2778113)

抗原

See all PARP3 抗体
PARP3 (Poly (ADP-Ribose) Polymerase Family, Member 3 (PARP3))

适用

人, 小鼠, 大鼠, 马, 兔, Cow, 犬, Pig

宿主

  • 46
  • 3
  • 1

克隆类型

  • 49
  • 1
多克隆

标记

  • 27
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PARP3 antibody is un-conjugated

应用范围

  • 36
  • 19
  • 14
  • 13
  • 13
  • 9
  • 4
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 15
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    序列

    LGREHHINTD NPSLKSPPPG FDSVIARGHT EPDPTQDTEL ELDGQQVVVP

    预测反应

    Cow: 92%, Dog: 91%, Horse: 100%, Human: 100%, Mouse: 77%, Pig: 85%, Rabbit: 100%, Rat: 92%

    产品特性

    This is a rabbit polyclonal antibody against PARP3. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human PARP3
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 532 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Augustin, Spenlehauer, Dumond, Ménissier-De Murcia, Piel, Schmit, Apiou, Vonesch, Kock, Bornens, De Murcia: "PARP-3 localizes preferentially to the daughter centriole and interferes with the G1/S cell cycle progression." in: Journal of cell science, Vol. 116, Issue Pt 8, pp. 1551-62, (2003) (PubMed).

  • 抗原

    PARP3 (Poly (ADP-Ribose) Polymerase Family, Member 3 (PARP3))

    别名

    PARP3

    背景

    PARP3 belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. PARP3 is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified.
    Alias Symbols: IRT1, ADPRT3, ADPRTL2, ADPRTL3, PADPRT-3
    Protein Interaction Partner: UBC, APP, PARP3, HIST1H1A, PARP1, HIST2H3C, MTHFD2, HIST2H2BE, RPA3,
    Protein Size: 532

    分子量

    59 kDa

    基因ID

    10039

    NCBI登录号

    NM_005485, NP_005476

    UniProt

    Q9Y6F1
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