PARP16 抗体 (Middle Region)
(1 reference)Our Local Distributor
北京 101111
Quick Overview for PARP16 抗体 (Middle Region) (ABIN2778107)
抗原
See all PARP16 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Middle Region
-
原理
- PARP16 Antibody - middle region
-
序列
- PKYFVVTNNQ LLRVKYLLVY SQKPPKSRAS SQLSWFSSHW FTVMISLYLL
-
预测反应
- Cow: 79%, Dog: 86%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 80%, Rabbit: 86%, Rat: 86%
-
产品特性
- This is a rabbit polyclonal antibody against PARP16. It was validated on Western Blot using a cell lysate as a positive control.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human PARP16
-
-
anti-Poly (ADP-Ribose) Polymerase Family, Member 16 (PARP16) (AA 215-244), (C-Term) antibody
PARP16 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB26311 unconjugated
anti-Poly (ADP-Ribose) Polymerase Family, Member 16 (PARP16) antibodyPARP16 适用: 人, 小鼠, 大鼠 IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase Family, Member 16 (PARP16) (AA 120-170) antibodyPARP16 适用: 人 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase Family, Member 16 (PARP16) (N-Term) antibodyPARP16 适用: 人, 小鼠, 大鼠, 豚鼠, 马, Cow, 犬, Pig, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase Family, Member 16 (PARP16) (AA 35-84) antibodyPARP16 适用: 人, 小鼠, 大鼠, 豚鼠, 马, Cow, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase Family, Member 16 (PARP16) (AA 252-301) antibodyPARP16 适用: 人, 小鼠, 大鼠, 豚鼠, 马, 犬, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase Family, Member 16 (PARP16) (AA 1-323) antibodyPARP16 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
说明
-
We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8108440
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.5 mg/mL
-
缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- prevent freeze-thaw cycles
-
储存条件
- 4 °C,-20 °C
-
储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
-
-
: "PARP16/ARTD15 is a novel endoplasmic-reticulum-associated mono-ADP-ribosyltransferase that interacts with, and modifies karyopherin-ß1." in: PLoS ONE, Vol. 7, Issue 6, pp. e37352, (2012) (PubMed).
-
-
- PARP16 (Poly (ADP-Ribose) Polymerase Family, Member 16 (PARP16))
-
别名
- PARP16
-
背景
-
Background Information: Poly(ADP-ribosyl)ation is an immediate DNA-damage-dependent post-translational modification of histones and other nuclear proteins that contributes to the survival of injured proliferating cells. PARP16 is a member of poly(ADP-ribose) polymerases (PARPs) family that is encoded by different genes and displaying a conserved catalytic domain in which PARP-1 (113 kDa), the founding member, and PARP-2 (62 kDa) are so far the sole enzymes whose catalytic activity has been shown to be immediately stimulated by DNA strand breaks. A large repertoire of sequences encoding novel PARPs now extends considerably the field of poly(ADP-ribosyl)ation reactions to various aspects of the cell biology including cell proliferation and cell death. Some of these new members interact with each other, share common partners and common subcellular localizations suggesting possible fine tuning in the regulation of this post-translational modification of proteins.
Gene Name: Poly (ADP-ribose) polymerase family, member 16
Alternative Symbols: ARTD15, pART15, C15orf30
Protein Name: Mono [ADP-ribose] polymerase PARP16
-
分子量
- 36 kDa
-
基因ID
- 54956
-
NCBI登录号
- NP_060321
-
UniProt
- Q8N5Y8
抗原
-
