FOXP2 抗体 (N-Term)
Quick Overview for FOXP2 抗体 (N-Term) (ABIN2778104)
抗原
See all FOXP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- SGLKSPKSSD KQRPLQVPVS VAMMTPQVIT PQQMQQILQQ QVLSPQQLQA
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特异性
- Isoform 4 and 5
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预测反应
- Dog: 100%, Goat: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 82%
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产品特性
- This is a rabbit polyclonal antibody against FOXP2. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human FOXP2
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 715 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- FOXP2 (Forkhead Box P2 (FOXP2))
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别名
- FOXP2
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背景
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FOXP2 is an evolutionarily conserved transcription factor expressed in fetal and adult brain. This transcription factor is a member of the forkhead/winged-helix (FOX) family of transcription factors, and contains a FOX DNA-binding domain and a large polyglutamine tract. Members of the FOX family of transcription factors are regulators of embryogenesis. The product of this gene is thought to be required for proper development of speech and language regions of the brain during embryogenesis. Although a point mutation in this gene has been associated with the KE pedigree segregating developmental verbal dyspraxia, no association between mutations in this gene and another speech disorder, autism, has been found. Four alternative transcripts encoding three different isoforms have been identified.
Alias Symbols: SPCH1, CAGH44, TNRC10
Protein Interaction Partner: FAM124A, TSACC, RPIA, SP4, SDCBP, PIN1, CTBP2, CTBP1, CCNC, AES, MAPK3, HSP90AA1, GATAD2B, FOXP1, FOXP4, FOXP2,
Protein Size: 715 -
分子量
- 80 kDa
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基因ID
- 93986
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NCBI登录号
- NM_014491, NP_055306
抗原
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