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GTF2IRD1 抗体 (C-Term)

This anti-GTF2IRD1 antibody is a 兔 多克隆 antibody detecting GTF2IRD1 in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, 犬, Cow, 马, 兔 和 豚鼠.
产品编号 ABIN2778093
发货至: 中国

Quick Overview for GTF2IRD1 抗体 (C-Term) (ABIN2778093)

抗原

See all GTF2IRD1 抗体
GTF2IRD1 (General Transcription Factor II I Repeat Domain-Containing 1 (GTF2IRD1))

适用

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人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠

宿主

  • 36
  • 8
  • 1

克隆类型

  • 40
  • 5
多克隆

标记

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This GTF2IRD1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    C-Term

    序列

    TFGSQNLERI LAVADKIKFT VTRPFQGLIP KPDEDDANRL GEKVILREQV

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against GTF2IRD1. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human GTF2IRD1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 959 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    GTF2IRD1 (General Transcription Factor II I Repeat Domain-Containing 1 (GTF2IRD1))

    别名

    GTF2IRD1

    背景

    GTF2IRD1 contains five GTF2I-like repeats and each repeat possesses a potential helix-loop-helix (HLH) motif. It may have the ability to interact with other HLH-proteins and function as a transcription factor or as a positive transcriptional regulator under the control of Retinoblastoma protein. GTF2IRD1 is related to Williams-Beuren syndrome, a multisystem developmental disorder. Western blots using three different antibodies against three unique regions of this protein target confirm the same apparent molecular weight in our tests. The protein encoded by this gene contains five GTF2I-like repeats and each repeat possesses a potential helix-loop-helix (HLH) motif. It may have the ability to interact with other HLH-proteins and function as a transcription factor or as a positive transcriptional regulator under the control of Retinoblastoma protein. This gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by deletion of multiple genes at 7q11.23. Alternative splicing of this gene generates at least 2 transcript variants.
    Alias Symbols: CREAM1, GTF3, MUSTRD1, RBAP2, WBSCR11, WBSCR12, hMusTRD1alpha1, BEN, WBS
    Protein Interaction Partner: UBC, SUMO2, USF1, HDAC3, SMAD2, EXOSC4, CDK20, PIAS2, SMAD3, NFI1,
    Protein Size: 959

    分子量

    106 kDa

    基因ID

    9569

    NCBI登录号

    NM_016328, NP_057412

    UniProt

    Q9UHL9
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