CLOCK 抗体 (N-Term)
Quick Overview for CLOCK 抗体 (N-Term) (ABIN2778091)
抗原
See all CLOCK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- LFTVSCSKMS SIVDRDDSSI FDGLVEEDDK DKAKRVSRNK SEKKRRDQFN
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预测反应
- Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 93%
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产品特性
- This is a rabbit polyclonal antibody against CLOCK. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human CLOCK
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 846 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CLOCK (Clock Homolog (Mouse) (CLOCK))
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别名
- CLOCK
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背景
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CLOCK is a protein that belongs to the basic helix-loop-helix (bHLH) family of transcription factors. Polymorphisms within the encoded protein have been associated with circadian rhythm sleep disorders. A similar protein in mice is a circadian regulator that acts as a transcription factor and forms a heterodimer with aryl hydrocarbon receptor nuclear translocator-like to activate transcription of mouse period 1.This gene encodes a protein that belongs to the basic helix-loop-helix (bHLH) family of transcription factors. Polymorphisms within the encoded protein have been associated with circadian rhythm sleep disorders. A similar protein in mice is a circadian regulator that acts as a transcription factor and forms a heterodimer with aryl hydrocarbon receptor nuclear translocator-like to activate transcription of mouse period 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: KAT13D, KIAA0334, bHLHe8
Protein Interaction Partner: SIRT1, ARNTL, SOX2, TFAP4, UBC, ARNTL2, PER3, RXRA, RARA, KAT2B, EP300,
Protein Size: 846 -
分子量
- 95 kDa
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基因ID
- 9575
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NCBI登录号
- NM_004898, NP_004889
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UniProt
- O15516
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途径
- Regulation of Lipid Metabolism by PPARalpha, Photoperiodism
抗原
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