MLL4 抗体 (N-Term)
Quick Overview for MLL4 抗体 (N-Term) (ABIN2778080)
抗原
See all MLL4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- WAGPRVQRGR GRGRGRGWGP SRGCVPEEES SDGESDEEEF QGFHSDEDVA
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预测反应
- Cow: 92%, Dog: 85%, Guinea Pig: 92%, Horse: 83%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 92%, Yeast: 91%
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产品特性
- This is a rabbit polyclonal antibody against MLL4. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human MLL4
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 582 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MLL4 (Histone-Lysine N-Methyltransferase MLL4 (MLL4))
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别名
- MLL4
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背景
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MLL4 a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET (suppressor of variegation, enhancer of zeste, and trithorax) domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL (mixed-lineage leukemia) family. MLL4 is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer
Alias Symbols: HRX2, MLL2, TRX2, WBP7, MLL4
Protein Interaction Partner: UBC, SMAD3, ZNF512B, ATXN1, HIST2H3C, WDR5, ASH2L, RBBP5, SEPT8, RPP14, NREP, TSC22D1, TK1, SMN1, RAP1B, PIN1, GRB7, RCC1, CDKN1A, ATP1B1, ANXA7, ANXA1, BCL6, WDR82, PAGR1, PAXIP1, NCOA6, SMARCB1, PRPF40A,
Protein Size: 582 -
分子量
- 64 kDa
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基因ID
- 9757
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Warburg Effect
抗原
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