DKFZp686M216 (N-Term) 抗体
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北京 101111
Quick Overview for DKFZp686M216 (N-Term) 抗体 (ABIN2778072)
抗原
适用
宿主
克隆类型
应用范围
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抗原表位
- N-Term
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序列
- VTLPVAPMAA TGQVRMAGAM PARGGKRRSG MDFDDEDGEG PSKFSRENHS
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特异性
- This antibody is specific to both isoforms of hARNT2.
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against DKFZp686M216. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human DKFZp686M216
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- DKFZp686M216
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背景
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This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting addition roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively.
Alias Symbols: bHLHe1, DKFZp686M216
Protein Interaction Partner: TRIM42, CEP57L1, RFX6, MIPOL1, DYDC1, SSX2IP, DTX2, SYCE1, RIMBP3, ZNF341, LZTS2, USHBP1, CEP63, CCDC33, NPAS3, RINT1, NDE1, ADAMTSL4, MTUS2, IKZF3, RBCK1, SPAG5, TACC3, CALCOCO2, SORBS3, PDE4DIP, TRAF4, BZRAP1, TFIP11, SSBP3, DGCR6, NCOA3, TRIP6, TRAF2,
Protein Size: 717 -
分子量
- 79 kDa
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基因ID
- 9915
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UniProt
- Q9HBZ2
抗原
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