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Claudin 11 抗体 (C-Term)

The 兔 多克隆 anti-Claudin 11 antibody (ABIN2778048) specifically detects Claudin 11 in WB 和 IHC. The antibody is reactive with 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠 和 马 samples.
产品编号 ABIN2778048
发货至: 中国
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Quick Overview for Claudin 11 抗体 (C-Term) (ABIN2778048)

抗原

See all Claudin 11 (CLDN11) 抗体
Claudin 11 (CLDN11)

适用

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人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 马

宿主

  • 51

克隆类型

  • 40
  • 11
多克隆

标记

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This Claudin 11 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    C-Term

    序列

    VSFGYSLYAG WIGAVLCLVG GCVILCCAGD AQAFGENRFY YTAGSSSPTH

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 86%

    产品特性

    This is a rabbit polyclonal antibody against CLDN11. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human CLDN11
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 207 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    Claudin 11 (CLDN11)

    别名

    CLDN11

    背景

    CLDN11 belongs to the claudin family of tight junction associated proteins and is a major component of central nervous system myelin that is necessary for normal CNS function. There is growing evidence that the protein determines the permeability between layers of myelin sheaths via focal adhesion and, with its expression highly regulated during development, may play an important role in cellular proliferation and migration. In addition, the protein is a candidate autoantigen in the development of autoimmune demyelinating disease.The protein encoded by this gene belongs to the claudin family of tight junction associated proteins and is a major component of central nervous system myelin that is necessary for normal CNS function. There is growing evidence that the protein determines the permeability between layers of myelin sheaths via focal adhesion and, with its expression highly regulated during development, may play an important role in cellular proliferation and migration. In addition, the protein is a candidate autoantigen in the development of autoimmune demyelinating disease.
    Alias Symbols: OSP, OTM
    Protein Interaction Partner: UBC, TSPAN3, TSPAN4,
    Protein Size: 207

    分子量

    22 kDa

    基因ID

    5010

    NCBI登录号

    NM_005602, NP_005593

    UniProt

    O75508

    途径

    Hepatitis C
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