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Claudin 19 抗体 (C-Term)

This anti-Claudin 19 antibody is a 兔 多克隆 antibody detecting Claudin 19 in WB. Suitable for 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, Pig, 兔 和 马.
产品编号 ABIN2778043
发货至: 中国

Quick Overview for Claudin 19 抗体 (C-Term) (ABIN2778043)

抗原

See all Claudin 19 (CLDN19) 抗体
Claudin 19 (CLDN19)

适用

人, 大鼠, 小鼠, Cow, 犬, 豚鼠, Pig, 兔, 马

宿主

  • 31
  • 3

克隆类型

  • 32
  • 2
多克隆

标记

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This Claudin 19 antibody is un-conjugated

应用范围

  • 13
  • 13
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  • 11
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  • 1
Western Blotting (WB)
  • 抗原表位

    • 15
    • 4
    • 2
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    • 1
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    • 1
    C-Term

    序列

    AVLGGSFLCC TCPEPERPNS SPQPYRPGPS AAAREPVVKL PASAKGPLGV

    预测反应

    Cow: 86%, Dog: 100%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 79%, Pig: 100%, Rabbit: 100%, Rat: 93%

    产品特性

    This is a rabbit polyclonal antibody against CLDN19. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human CLDN19
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 224 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    Claudin 19 (CLDN19)

    别名

    CLDN19

    背景

    CLDN19 belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Defects in this gene are the cause of hypomagnesemia renal with ocular involvement (HOMGO). HOMGO is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia and nystagmus. The product of this gene belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Defects in this gene are the cause of hypomagnesemia renal with ocular involvement (HOMGO). HOMGO is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia and nystagmus. Two transcript variants encoding distinct isoforms have been identified for this gene.
    Alias Symbols: HOMG5
    Protein Interaction Partner: SRPK2,
    Protein Size: 224

    分子量

    23 kDa

    基因ID

    149461

    NCBI登录号

    NM_148960, NP_683763

    UniProt

    Q8N6F1

    途径

    Cell-Cell Junction Organization, Hepatitis C
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