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Tumor Protein p73 抗体 (N-Term)

Name: Tumor Protein p73 抗体 (N-Term)
SKU: ABIN2777952
Availability: OutOfStock

This anti-Tumor Protein p73 antibody is a 兔多克隆 antibody detecting Tumor Protein p73 in WB. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 斑马鱼和 Pig.

WB Suggested Anti-TP73 Antibody Titration: 0. (Tumor Protein p73 抗体 (N-Term))

Host: Rabbit Target Name: TP73 Sample Type: Human Fetal Muscle Antibody Dilution: 1. (Tumor Protein p73 抗体 (N-Term))

WB Suggested Anti-TP73 Antibody Positive Control: Lane1: 10ug untransfected H1299, Lane2: 10ug GFP-TAp73 transfected H1299, Lane3: 10ug GFP-DNp73 transfected H1299, Lane4: 10ug GFP-DBDp73 transfected H1299 Primary Antibody Dilution : 1:1000 Secondary Antibody : Anti-rabbit-HRP Secondry Antibody Dilution : 1:5000 Submitted by: Francesca Grespi, VIB-Department for Molecular Biomedical Research, University of Gent (Tumor Protein p73 抗体 (N-Term))

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产品编号 ABIN2777952

发货至: 中国

Datasheet as PDF

Quick Overview for Tumor Protein p73 抗体 (N-Term) (ABIN2777952)

抗原

See all Tumor Protein p73 (TP73) 抗体

Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))

适用

人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 斑马鱼, Pig

宿主

兔

克隆类型

多克隆

标记

This Tumor Protein p73 antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product TP73 Primary Antibody

抗原表位
25

15

9

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3

3

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2

2

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2

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1

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1

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1

1

1
N-Term

序列

AQSTATSPDG GTTFEHLWSS LEPDSTYFDL PQSSRGNNEV VGGTDSSMDV

预测反应

Cow: 100%, Dog: 100%, Guinea Pig: 86%, Human: 100%, Mouse: 93%, Pig: 92%, Rat: 93%, Zebrafish: 92%

产品特性

This is a rabbit polyclonal antibody against TP73. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human TP73
anti-Tumor Protein P73 (TP73) (AA 167-409) antibody
TP73 适用: 人 WB, IHC, IHC (p), IF 宿主: 小鼠 Monoclonal 2H5 unconjugated

anti-Tumor Protein P73 (TP73) (acLys321) antibody
TP73 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Tumor Protein P73 (TP73) (Tyr221) antibody
TP73 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Tumor Protein P73 (TP73) (pTyr99) antibody
TP73 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Tumor Protein P73 (TP73) (AA 1-198) antibody
TP73 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Tumor Protein P73 (TP73) (AA 288-317) antibody
TP73 适用: 人, 小鼠 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated

anti-Tumor Protein P73 (TP73) (AA 1-198) antibody
TP73 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Tumor Protein P73 (TP73) (AA 501-631) antibody
TP73 适用: 人, 小鼠, 大鼠 ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Tumor Protein P73 (TP73) (AA 167-409) antibody
TP73 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2H2 unconjugated

anti-Tumor Protein P73 (TP73) (AA 1-100) antibody
TP73 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 636 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
抗原

Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))

别名

TP73

背景

TP73 belongs to the p53 family. It participates in the apoptotic response to DNA damage. When overproduced, it activates transcription from p53-responsive promoters and induces apoptosis. TP53 may be a tumor suppressor protein. This gene encodes tumor protein p73, which is a member of the p53 family of transcription factors involved in cellular responses to stress and development. The family members include p53, p63, and p73 and have high sequence similarity to one another, which allows p63 and p73 to transactivate p53-responsive genes causing cell cycle arrest and apoptosis. The family members can interact with each other in many ways involving direct or indirect protein interactions, resulting in regulation of the same target gene promoters or regulation of each other's promoters. The p73 protein is expressed at very low levels in normal tissues and is differentially expressed in a number of tumors. The p73 gene expresses at least 35 mRNA variants due to the use of alternate promoters, alternate translation initiation sites, and multiple splice variations. Theoretically this can account for 29 different p73 isoforms, however, the biological validity and the full-length nature of most variants have not been determined.
Alias Symbols: P73
Protein Interaction Partner: FUS, YAP1, WWOX, UBC, TRIM32, SOX2, PFDN5, MYC, EP300, CDK2, CCNE1, CCNB1, CCNA2, CCND1, XPO1, PIN1, AURKA, PRKACA, MAD2L1, HSPA9, CDC20, TP53BP1, RBX1, DDB1, RCHY1, KAT2B, NEDD8, MDM2, IKBKB, DAXX, CHUK, BUB1B, BRCA1, TNK2, AMPH, CREBBP, KAT5, CEP131, MD
Protein Size: 636

分子量

69 kDa

基因ID

7161

NCBI登录号

NM_005427, NP_005418

UniProt

O15350

途径

Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus