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TEAD4 抗体 (Middle Region)

Cited in 1 publication. This anti-TEAD4 antibody is a 兔 多克隆 antibody detecting TEAD4 in WB 和 IF. Suitable for 人, 小鼠, 大鼠, 豚鼠, 马, 兔, Cow 和 犬.
产品编号 ABIN2777935
发货至: 中国
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Quick Overview for TEAD4 抗体 (Middle Region) (ABIN2777935)

抗原

See all TEAD4 抗体
TEAD4 (TEA Domain Family Member 4 (TEAD4))

适用

  • 48
  • 24
  • 21
  • 5
  • 5
  • 5
  • 4
  • 4
  • 4
  • 3
  • 1
  • 1
人, 小鼠, 大鼠, 豚鼠, 马, 兔, Cow, 犬

宿主

  • 40
  • 8

克隆类型

  • 40
  • 8
多克隆

标记

  • 27
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This TEAD4 antibody is un-conjugated

应用范围

  • 44
  • 13
  • 12
  • 8
  • 6
  • 6
  • 4
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    序列

    LVKFWADLNT NIEDEGSSFY GVSSQYESPE NMIITCSTKV CSFGKQVVEK

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 85%, Rabbit: 100%, Rat: 77%

    产品特性

    This is a rabbit polyclonal antibody against TEAD4. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human TEAD4
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 391 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Chan, Lim, Loo, Chong, Huang, Hong: "TEADs mediate nuclear retention of TAZ to promote oncogenic transformation." in: The Journal of biological chemistry, Vol. 284, Issue 21, pp. 14347-58, (2009) (PubMed).

  • 抗原

    TEAD4 (TEA Domain Family Member 4 (TEAD4))

    别名

    TEAD4

    背景

    TEAD4 is a member of the transcriptional enhancer factor (TEF) family of transcription factors, which contain the TEA/ATTS DNA-binding domain. TEAD4 is preferentially expressed in the skeletal muscle, and binds to the M-CAT regulatory element found in promoters of muscle-specific genes to direct their gene expression. Alternatively spliced transcripts encoding distinct isoforms, some of which are translated through the use of a non-AUG (UUG) initiation codon, have been described for this protein.This gene product is a member of the transcriptional enhancer factor (TEF) family of transcription factors, which contain the TEA/ATTS DNA-binding domain. It is preferentially expressed in the skeletal muscle, and binds to the M-CAT regulatory element found in promoters of muscle-specific genes to direct their gene expression. Alternatively spliced transcripts encoding distinct isoforms, some of which are translated through the use of a non-AUG (UUG) initiation codon, have been described for this gene.
    Alias Symbols: EFTR-2, MGC9014, RTEF1, TCF13L1, TEF-3, TEFR-1, hRTEF-1B, TEF3
    Protein Interaction Partner: CCDC172, SSX2IP, LZTS2, CEP70, CEP55, RABGEF1, CCNDBP1, KIAA0753, PNMA1, TRAF1, VPS52, TRIM27, GOLGA2, UBC, SUMO2, CCDC85B, WWTR1, YAP1, VGLL1, MYH7,
    Protein Size: 391

    分子量

    44 kDa

    基因ID

    7004

    NCBI登录号

    NM_201441, NP_958849

    UniProt

    Q15561

    途径

    Regulation of Lipid Metabolism by PPARalpha
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