T-Box 5 抗体 (N-Term)
(3 references)Quick Overview for T-Box 5 抗体 (N-Term) (ABIN2777915)
抗原
See all T-Box 5 (TBX5) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- NSMHKYQPRL HIVKADENNG FGSKNTAFCT HVFPETAFIA VTSYQNHKIT
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预测反应
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against TBX5. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human TBX5
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anti-T-Box 5 (TBX5) (AA 402-518) antibody
TBX5 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 1G10 unconjugated
anti-T-Box 5 (TBX5) (AA 174-223) antibodyTBX5 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 兔, Cow, 马, 斑马鱼, 山羊, 绵羊, Bat, Hamster, 猴, Pig, 小鸡, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-T-Box 5 (TBX5) (AA 1-518) antibodyTBX5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-T-Box 5 (TBX5) (AA 249-298) antibodyTBX5 适用: 人, 犬, 豚鼠, 兔, Cow, Bat, Hamster, 猴, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-T-Box 5 (TBX5) antibodyTBX5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 7B11 unconjugated
anti-T-Box 5 (TBX5) antibodyTBX5 适用: 人, 小鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-T-Box 5 (TBX5) (AA 124-173) antibodyTBX5 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 兔, Cow, 马, 斑马鱼, 山羊, 绵羊, Bat, Hamster, 猴, Pig, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-T-Box 5 (TBX5) (AA 1-70) antibodyTBX5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 518 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Holt-Oram syndrome with intermediate atrioventricular canal defect, and aortic coarctation: functional characterization of a de novo TBX5 mutation." in: American journal of medical genetics. Part A, Vol. 164A, Issue 6, pp. 1419-24, (2014) (PubMed).
: "Phenanthrene exposure causes cardiac arrhythmia in embryonic zebrafish via perturbing calcium handling." in: Aquatic toxicology (Amsterdam, Netherlands), Vol. 142-143, pp. 26-32, (2013) (PubMed).
: "Induction of apoptosis and inhibition of cell growth by tbx5 knockdown contribute to dysmorphogenesis in Zebrafish embryos." in: Journal of biomedical science, Vol. 18, pp. 73, (2011) (PubMed).
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: "Holt-Oram syndrome with intermediate atrioventricular canal defect, and aortic coarctation: functional characterization of a de novo TBX5 mutation." in: American journal of medical genetics. Part A, Vol. 164A, Issue 6, pp. 1419-24, (2014) (PubMed).
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- T-Box 5 (TBX5)
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别名
- TBX5
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背景
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TBX5 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. TBX5 is closely linked to related family member T-box 3 (ulnar mammary syndrome) on human chromosome 12. The encoded protein may play a role in heart development and specification of limb identity. Mutations in TBX5 have been associated with Holt-Oram syndrome, a developmental disorder affecting the heart and upper limbs. Several transcript variants encoding different isoforms have been described for TBX5.
Alias Symbols: HOS
Protein Interaction Partner: KDM6A, SMARCA4, KAT5, GATA4, NKX2-5,
Protein Size: 518 -
分子量
- 58 kDa
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基因ID
- 6910
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NCBI登录号
- NM_000192, NP_000183
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UniProt
- Q99593
抗原
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