T-Box 1 抗体 (Middle Region)
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北京 101111
Quick Overview for T-Box 1 抗体 (Middle Region) (ABIN2777911)
抗原
See all T-Box 1 (TBX1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- PVASPTQPSG TEKGGHVLKD KEVKAETSRN TPEREVELLR DAGGCVNLGL
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预测反应
- Guinea Pig: 85%, Horse: 77%, Human: 100%, Mouse: 77%, Rabbit: 85%, Rat: 85%
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产品特性
- This is a rabbit polyclonal antibody against TBX1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human TBX1
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anti-T-Box 1 (TBX1) (AA 327-356), (C-Term) antibody
TBX1 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB22154 unconjugated
anti-T-Box 1 (TBX1) (C-Term) antibodyTBX1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-T-Box 1 (TBX1) antibodyTBX1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-T-Box 1 (TBX1) (C-Term) antibodyTBX1 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-T-Box 1 (TBX1) (AA 396-445) antibodyTBX1 适用: 人, 小鼠, 大鼠, 豚鼠, 兔, 犬 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-T-Box 1 (TBX1) (C-Term) antibodyTBX1 适用: 人 WB, IF, IHC, IC 宿主: 兔 Polyclonal unconjugated
anti-T-Box 1 (TBX1) (C-Term) antibodyTBX1 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-T-Box 1 (TBX1) (AA 22-107) antibodyTBX1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-T-Box 1 (TBX1) (AA 327-356) antibodyTBX1 适用: 人 WB, IF, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-T-Box 1 (TBX1) (AA 324-373) antibodyTBX1 适用: 人, 小鼠, 大鼠, 豚鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 398 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- T-Box 1 (TBX1)
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别名
- TBX1
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背景
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TBX1 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. TBX1 product shares 98 % amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where TBX1 has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product shares 98 % amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where this gene has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: CAFS, CTHM, DGCR, DGS, DORV, TBX1C, TGA, VCFS
Protein Interaction Partner: TERF2, TERF1,
Protein Size: 398 -
分子量
- 43 kDa
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基因ID
- 6899
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NCBI登录号
- NM_080646, NP_542377
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UniProt
- O43435
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途径
- Retinoic Acid Receptor Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation
抗原
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