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STAT4 抗体 (N-Term)

Cited in 1 publication. This 兔 多克隆 anti-STAT4 antibody specifically detects STAT4 in WB 和 IHC. The antibody is reactive with 人, 小鼠, 大鼠, Pig, 犬, 兔 和 马 samples.
产品编号 ABIN2777897
发货至: 中国
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Quick Overview for STAT4 抗体 (N-Term) (ABIN2777897)

抗原

See all STAT4 抗体
STAT4 (Signal Transducer and Activator of Transcription 4 (STAT4))

适用

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人, 小鼠, 大鼠, Pig, 犬, 兔, 马

宿主

  • 103
  • 8
  • 2

克隆类型

  • 75
  • 38
多克隆

标记

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This STAT4 antibody is un-conjugated

应用范围

  • 93
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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 28
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    N-Term

    序列

    IGGPLHNGLD QLQNCFTLLA ESLFQLRRQL EKLEEQSTKM TYEGDPIPMQ

    预测反应

    Dog: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 100%, Rat: 92%

    产品特性

    This is a rabbit polyclonal antibody against STAT4. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human STAT4
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 748 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Torpey, Maher, Bothwell, Pober: "Interferon alpha but not interleukin 12 activates STAT4 signaling in human vascular endothelial cells." in: The Journal of biological chemistry, Vol. 279, Issue 25, pp. 26789-96, (2004) (PubMed).

  • 抗原

    STAT4 (Signal Transducer and Activator of Transcription 4 (STAT4))

    别名

    STAT4

    背景

    STAT4 is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells.
    Alias Symbols: SLEB11
    Protein Interaction Partner: UBC, ADRB2, TRIM28, FHL1, ZNF467, PIAS2, NMI, IL12RB2, IL12RB1, MAP2K6, STAT4, MAPK14, CREBBP, JUN, STAT3, IFNGR1,
    Protein Size: 748

    分子量

    86 kDa

    基因ID

    6775

    NCBI登录号

    NM_003151, NP_003142

    UniProt

    Q14765

    途径

    JAK/STAT Signaling
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