ING3 抗体 (Middle Region)
Quick Overview for ING3 抗体 (Middle Region) (ABIN2777878)
抗原
See all ING3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- LSSGTGAGAI TMAAAQAVQA TAQMKEGRRT SSLKASYEAF KNNDFQLGKE
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 75%, Zebrafish: 92%
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产品特性
- This is a rabbit polyclonal antibody against ING3. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human ING3
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anti-Inhibitor of Growth Family, Member 3 (ING3) (AA 1-92) antibody
ING3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2C4 unconjugated
anti-Inhibitor of Growth Family, Member 3 (ING3) (AA 51-223) antibodyING3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Inhibitor of Growth Family, Member 3 (ING3) (Internal Region) antibodyING3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Inhibitor of Growth Family, Member 3 (ING3) (AA 1-92) antibodyING3 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Inhibitor of Growth Family, Member 3 (ING3) (AA 216-265) antibodyING3 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 小鸡, 猴, Bat, Pig, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Inhibitor of Growth Family, Member 3 (ING3) (AA 36-85) antibodyING3 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 斑马鱼, 小鸡, 猴, Bat, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Inhibitor of Growth Family, Member 3 (ING3) antibodyING3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Inhibitor of Growth Family, Member 3 (ING3) (AA 1-92) antibodyING3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E21 unconjugated
anti-Inhibitor of Growth Family, Member 3 (ING3) (AA 1-92) antibodyING3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Inhibitor of Growth Family, Member 3 (ING3) (N-Term) antibodyING3 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 418 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ING3 (Inhibitor of Growth Family, Member 3 (ING3))
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别名
- ING3
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背景
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ING3 is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers.The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been observed.
Alias Symbols: Eaf4, FLJ20089, ING2, p47ING3, MEAF4
Protein Interaction Partner: USHBP1, TRIM54, TEX11, FBXO25, APP, H2AFZ, ELAVL1, NR1H3, NR1H2, DMAP1, MORF4L1, KAT5, RBX1, RUVBL1, CUL1, TRRAP, UBC, SKP2, ACTL6A, EPC1, HHT2, HHT1, MEAF6, EPC2, BRD8, RUVBL2, YEATS4,
Protein Size: 418 -
分子量
- 47 kDa
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基因ID
- 54556
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NCBI登录号
- NM_019071, NP_061944
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UniProt
- Q9NXR8
抗原
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