EPC1 抗体 (Middle Region)
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北京 101111
Quick Overview for EPC1 抗体 (Middle Region) (ABIN2777875)
抗原
See all EPC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- EPC1 Antibody - middle region
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序列
- VNKQDKADLI RPKRKYEKKP KVLPSSAAAT PQQTSPAALP VFNAKDLNQY
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against EPC1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human EPC1
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP33343-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- EPC1 (Enhancer of Polycomb Homolog 1 (EPC1))
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别名
- EPC1
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背景
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Background Information: EPC1 is a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage.
Gene Name: Enhancer of polycomb homolog 1 (Drosophila)
Alternative Symbols: Epl1
Protein Name: Enhancer of polycomb homolog 1
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分子量
- 93kDa
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基因ID
- 80314
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NCBI登录号
- NP_079485
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UniProt
- Q9H2F5
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途径
- Regulation of Muscle Cell Differentiation
抗原
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