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EPC1 抗体 (Middle Region)

This anti-EPC1 antibody is a 兔 多克隆 antibody detecting EPC1 in WB. Suitable for 人, 小鼠, Cow, 犬, 马, 兔, 大鼠, 豚鼠 和 Pig.
产品编号 ABIN2777875
发货至: 中国

Quick Overview for EPC1 抗体 (Middle Region) (ABIN2777875)

抗原

See all EPC1 抗体
EPC1 (Enhancer of Polycomb Homolog 1 (EPC1))

适用

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人, 小鼠, Cow, 犬, 马, 兔, 大鼠, 豚鼠, Pig

宿主

  • 17
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克隆类型

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多克隆

标记

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This EPC1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    Middle Region

    序列

    VNKQDKADLI RPKRKYEKKP KVLPSSAAAT PQQTSPAALP VFNAKDLNQY

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against EPC1. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human EPC1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 836 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    EPC1 (Enhancer of Polycomb Homolog 1 (EPC1))

    别名

    EPC1

    背景

    EPC1 is a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage.
    Alias Symbols: DKFZp781P2312, Epl1
    Protein Interaction Partner: RINT1, KRT15, Hopx, TRIM27, H2AFZ, DMAP1, ING3, MORF4L1, KAT5, MYC, MORF4L2, MRGBP, EED, EZH2, E2F6, SRF,
    Protein Size: 836

    分子量

    93 kDa

    基因ID

    80314

    NCBI登录号

    NM_025209, NP_079485

    UniProt

    Q9H2F5

    途径

    Regulation of Muscle Cell Differentiation
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