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BCL11B 抗体 (Middle Region)

This 兔 多克隆 anti-BCL11B antibody specifically detects BCL11B in WB 和 IHC. The antibody is reactive with 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠 和 马 samples.
产品编号 ABIN2777845
发货至: 中国
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Quick Overview for BCL11B 抗体 (Middle Region) (ABIN2777845)

抗原

See all BCL11B 抗体
BCL11B (B-Cell CLL/lymphoma 11B (Zinc Finger Protein) (BCL11B))

适用

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人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 马

宿主

  • 44
  • 2
  • 1

克隆类型

  • 35
  • 12
多克隆

标记

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This BCL11B antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 9
    • 7
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    Middle Region

    序列

    QASKLKRHMK THMHKAGSLA GRSDDGLSAA SSPEPGTSEL AGEGLKAADG

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against BCL11B. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human BCL11B
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 823 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    BCL11B (B-Cell CLL/lymphoma 11B (Zinc Finger Protein) (BCL11B))

    别名

    BCL11B

    背景

    BCL11B is the tumor-suppressor protein involved in T-cell lymphomas. BCL11B may function on the P53-signaling pathway. BCL11B may be a key regulator of both differentiation and survival during thymocyte development. BCL11B repress transcription through direct, TFCOUP2-independent binding to a GC-rich response element.This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported.
    Alias Symbols: CTIP-2, CTIP2, RIT1, hRIT1-alpha, ZNF856B
    Protein Interaction Partner: HDAC6, HDAC2, HDAC1, NOTCH1, UBC, HDAC3, SUV39H1, tat, CBX5, NR2F1, SP1, MBD3, MTA2, MTA1, RBBP7, RBBP4, CHD4, NR2F2,
    Protein Size: 823

    分子量

    88 kDa

    基因ID

    64919

    NCBI登录号

    NM_022898, NP_075049
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