SIAH2 抗体 (Middle Region)
Quick Overview for SIAH2 抗体 (Middle Region) (ABIN2777843)
抗原
See all SIAH2 抗体适用
宿主
克隆类型
标记
应用范围
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                                            抗原表位
- Middle Region
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                                            序列
- AVDWVMMQSC FGHHFMLVLE KQEKYEGHQQ FFAIVLLIGT RKQAENFAYR
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                                            预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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                                            产品特性
- This is a rabbit polyclonal antibody against SIAH2. It was validated on Western Blot using a cell lysate as a positive control.
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                                            纯化方法
- Affinity Purified
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                                            免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human SIAH2
 
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                                            应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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                                            说明
- 
                        Antigen size: 324 AA 
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                                            限制
- 仅限研究用
 
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                                            状态
- Liquid
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                                            浓度
- Lot specific
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                                            缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            注意事项
- Avoid repeated freeze-thaw cycles.
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                                            储存条件
- -20 °C
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                                            储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
 
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    - SIAH2 (Siah E3 Ubiquitin Protein Ligase 2 (SIAH2))
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                                            别名
- SIAH2
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                                            背景
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                        SIAH2 is a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in regulating cellular response to hypoxia.This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in regulating cellular response to hypoxia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
 Alias Symbols: hSiah2
 Protein Interaction Partner: EGLN3, XAF1, HIPK2, UBE2D1, UBE2L6, SIAH2, UBE2D3, UBC, PPP1R13B, TP53BP2, NFE2L2, USP19, AR, UBE2I, STAT3, MYD88, EEF1D, CCBE1, SETD2, HIPK3, TNK2, KAT5, KAT2B, UBE2D2, TPX2, PML, ATN1, PSMD4, PPP1R12A, EGLN2, SH3RF1, EGLN1, DYRK2, PPP1CC, AFF1, DCC, CEB
 Protein Size: 324
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                                            分子量
- 34 kDa
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                                            基因ID
- 6478
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                                            NCBI登录号
- NM_005067, NP_005058
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                                            UniProt
- O43255
 抗原
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