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RORC 抗体 (Middle Region)

This anti-RORC antibody is a 兔 多克隆 antibody detecting RORC in WB. Suitable for 人, 小鼠, 大鼠, Cow, 马, 兔 和 Pig. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2777822
发货至: 中国

Quick Overview for RORC 抗体 (Middle Region) (ABIN2777822)

抗原

See all RORC 抗体
RORC (RAR-Related Orphan Receptor C (RORC))

适用

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人, 小鼠, 大鼠, Cow, 马, 兔, Pig

宿主

  • 91
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  • 1
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克隆类型

  • 94
  • 21
多克隆

标记

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This RORC antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    Middle Region

    序列

    CHLEYSPERG KAEGRESFYS TGSQLTPDRC GLRFEEHRHP GLGELGQGPD

    预测反应

    Cow: 92%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 79%, Rat: 86%

    产品特性

    This is a rabbit polyclonal antibody against RORC. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human RORC
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 497 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Huang, Huang, Lee, Ng, Chang: "Postirradiation sinus mucosa disease in nasopharyngeal carcinoma patients." in: The Laryngoscope, Vol. 117, Issue 4, pp. 737-42, (2007) (PubMed).

  • 抗原

    RORC (RAR-Related Orphan Receptor C (RORC))

    别名

    RORC

    背景

    RORC encodes a protein which is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known, however, studies of a similar gene in mice have shown that RORC may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2.The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known, however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene. The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known, however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene.
    Alias Symbols: MGC129539, NR1F3, RORG, RZRG, TOR, RZR-GAMMA
    Protein Interaction Partner: EVI2A, NCOA6, EIF3I, CHD4, EIF4EBP1,
    Protein Size: 497

    分子量

    56 kDa

    基因ID

    6097

    NCBI登录号

    NM_001001523, NP_001001523

    UniProt

    B3KUU9

    途径

    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
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