RFXAP 抗体 (Middle Region)
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- 抗原 See all RFXAP 抗体
- RFXAP (Regulatory Factor X-Associated Protein (RFXAP))
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抗原表位
- Middle Region
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适用
- 人, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RFXAP antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- SDQALNCGGT ASTGSAGNVK LEESADNILS IVKQRTGSFG DRPARPTLLE
- 预测反应
- Guinea Pig: 100%, Human: 100%
- 产品特性
- This is a rabbit polyclonal antibody against RFXAP. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human RFXAP
- Top Product
- Discover our top product RFXAP Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 272 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- RFXAP (Regulatory Factor X-Associated Protein (RFXAP))
- 别名
- RFXAP (RFXAP 产品)
- 背景
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RFXAP is part of the RFX complex that binds to the X-box of MHC II promoters.Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated ankyrin-containing protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group D. Transcript variants utilizing different polyA signals have been found for this gene. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because transcript sequence consistent with the reference genome assembly was not available for all regions of the RefSeq transcript. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: -
Protein Interaction Partner: EPS8, NHP2L1, NCL, MLLT1, HDAC4, SMARCA4, RFXANK, RFX5,
Protein Size: 272 - 分子量
- 28 kDa
- 基因ID
- 5994
- NCBI登录号
- NM_000538, NP_000529
- UniProt
- O00287
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