SOX6 抗体 (Middle Region)
Quick Overview for SOX6 抗体 (Middle Region) (ABIN2777776)
抗原
See all SOX6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- YGMKTDGGSL AGNEMINGED EMEMYDDYED DPKSDYSSEN EAPEAVSAN
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预测反应
- Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
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产品特性
- This is a rabbit polyclonal antibody against SOX6. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human SOX6
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anti-SRY (Sex Determining Region Y)-Box 6 (SOX6) (AA 1-828) antibody
SOX6 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 6 (SOX6) (N-Term) antibodySOX6 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 6 (SOX6) (N-Term) antibodySOX6 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF, ChIP 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 6 (SOX6) (AA 1-74) antibodySOX6 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 6 (SOX6) (AA 1-109) antibodySOX6 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 6 (SOX6) (C-Term) antibodySOX6 适用: 人, 小鼠, 大鼠, 猴, Cow, 豚鼠, 马, Pig, 兔, 斑马鱼, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 6 (SOX6) (AA 1-74) antibodySOX6 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 6 (SOX6) (AA 1-20) antibodySOX6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 6 (SOX6) (C-Term) antibodySOX6 适用: 人, 猴, Cow, 犬, 豚鼠, 马, Pig, 兔, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 6 (SOX6) antibodySOX6 适用: 人 ICC, DB 宿主: 小鼠 Monoclonal 155C5a unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 804 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SOX6 (SRY (Sex Determining Region Y)-Box 6 (SOX6))
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别名
- SOX6
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背景
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SOX6 is a member of the D subfamily of sex determining region y-related transcription factors that are characterized by a conserved DNA-binding domain termed the high mobility group box and by their ability to bind the minor groove of DNA. SOX6 is a transcriptional activator that is required for normal development of the central nervous system, chondrogenesis and maintenance of cardiac and skeletal muscle cells. SOX6 interacts with other family members to cooperatively activate gene expression.Members of the SOX gene family, such as SOX6, encode transcription factors defined by the conserved high mobility group (HMG) DNA-binding domain. Unlike most transcription factors, SOX transcription factors bind to the minor groove of DNA, causing a 70- to 85-degree bend and introducing local conformational changes (Cohen-Barak et al., 2001 [PubMed 11255018]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-2696 AL136780.1 1-2696 2697-5158 AC009869.7 10394-12855
Alias Symbols: HSSOX6, SOXD
Protein Interaction Partner: TAF4, TRIP12, UBC, SOX2, POMGNT1, ZNF184, UBE2J1, SUMO1, SUMO2, SUMO3, HDAC1, CTNNB1, SOX5, CENPK, DAZAP2, SOX6, CTBP2,
Protein Size: 804 -
分子量
- 89 kDa
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基因ID
- 55553
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NCBI登录号
- NM_017508, NP_059978
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UniProt
- A8MRT1
抗原
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