SOX18 抗体 (Middle Region)
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北京 101111
Quick Overview for SOX18 抗体 (Middle Region) (ABIN2777725)
抗原
See all SOX18 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- RTAPPAAPLA GLYYGTLGTP GPYPGPLSPP PEAPPLESAE PLGPAADLWA
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预测反应
- Cow: 86%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against SOX18. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human SOX18
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anti-SRY (Sex Determining Region Y)-Box 18 (SOX18) (AA 63-150) antibody
SOX18 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1C4 unconjugated
anti-SRY (Sex Determining Region Y)-Box 18 (SOX18) (AA 153-377) antibodySOX18 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 18 (SOX18) (AA 271-320) antibodySOX18 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, Pig, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 18 (SOX18) (AA 63-150) antibodySOX18 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 18 (SOX18) (AA 192-241) antibodySOX18 适用: 人, 小鼠, 大鼠, 豚鼠, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 18 (SOX18) antibodySOX18 适用: 人 WB, IF/ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 384 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Lymphatic regulator PROX1 determines Schlemm's canal integrity and identity." in: The Journal of clinical investigation, Vol. 124, Issue 9, pp. 3960-74, (2014) (PubMed).
: "Endothelial ERK signaling controls lymphatic fate specification." in: The Journal of clinical investigation, Vol. 123, Issue 3, pp. 1202-15, (2013) (PubMed).
: "Genetic ablation of SOX18 function suppresses tumor lymphangiogenesis and metastasis of melanoma in mice." in: Cancer research, Vol. 72, Issue 12, pp. 3105-14, (2012) (PubMed).
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: "Lymphatic regulator PROX1 determines Schlemm's canal integrity and identity." in: The Journal of clinical investigation, Vol. 124, Issue 9, pp. 3960-74, (2014) (PubMed).
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- SOX18 (SRY (Sex Determining Region Y)-Box 18 (SOX18))
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别名
- SOX18
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背景
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SOX18 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. This protein plays a role in hair, blood vessel, and lymphatic vessel development. Mutations in this gene have been associated with recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia.
Alias Symbols: HLTS
Protein Interaction Partner: GKAP1, MECP2, MEF2C, HMGB1,
Protein Size: 384 -
分子量
- 41 kDa
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基因ID
- 54345
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NCBI登录号
- NM_018419, NP_060889
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UniProt
- P35713
抗原
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