KDM4C 抗体 (Middle Region)
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北京 101111
Quick Overview for KDM4C 抗体 (Middle Region) (ABIN2777688)
抗原
See all KDM4C 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- JMJD2C Antibody - C-terminal region
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序列
- CLCNLRGGAL KQTKNNKWAH VMCAVAVPEV RFTNVPERTQ IDVGRIPLQR
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against JMJD2C. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human JMJD2C
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anti-Lysine (K)-Specific Demethylase 4C (KDM4C) (AA 1023-1056), (C-Term) antibody
KDM4C 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB10796 unconjugated
anti-Lysine (K)-Specific Demethylase 4C (KDM4C) (C-Term) antibodyKDM4C 适用: 人, 小鼠, 大鼠, 猴, Cow, 犬, 马, 兔, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 4C (KDM4C) (AA 475-525) antibodyKDM4C 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 4C (KDM4C) (AA 450-600) antibodyKDM4C 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 4C (KDM4C) antibodyKDM4C 适用: 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 4C (KDM4C) antibodyKDM4C 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 4C (KDM4C) (AA 350-570) antibodyKDM4C 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 4C (KDM4C) (Internal Region) antibodyKDM4C 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP32974-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "IDH mutation impairs histone demethylation and results in a block to cell differentiation." in: Nature, Vol. 483, Issue 7390, pp. 474-8, (2012) (PubMed).
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- KDM4C (Lysine (K)-Specific Demethylase 4C (KDM4C))
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别名
- JMJD2C
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背景
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Background Information: JMJD2C is a member of the Jumonji domain 2 (JMJD2) family. It contains one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma.
Gene Name: Lysine (K)-specific demethylase 4C
Alternative Symbols: GASC1, JHDM3C, JMJD2C, TDRD14C
Protein Name: Lysine-specific demethylase 4C Ensembl ENSP00000445427
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分子量
- 92 kDa
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基因ID
- 23081
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NCBI登录号
- NP_001140167
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UniProt
- F5H347
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途径
- Nuclear Hormone Receptor Binding, Warburg Effect
抗原
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