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KDM4C 抗体 (C-Term)

This anti-KDM4C antibody is a 兔 多克隆 antibody detecting KDM4C in WB. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠 和 Pig. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2777688
发货至: 中国

Quick Overview for KDM4C 抗体 (C-Term) (ABIN2777688)

抗原

See all KDM4C 抗体
KDM4C (Lysine (K)-Specific Demethylase 4C (KDM4C))

适用

人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠, Pig

宿主

  • 40
  • 2

克隆类型

  • 40
  • 2
多克隆

标记

  • 21
  • 7
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This KDM4C antibody is un-conjugated

应用范围

  • 29
  • 15
  • 11
  • 9
  • 6
  • 5
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    C-Term

    序列

    CLCNLRGGAL KQTKNNKWAH VMCAVAVPEV RFTNVPERTQ IDVGRIPLQR

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against JMJD2C. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human JMJD2C
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 813 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Lu, Ward, Kapoor, Rohle, Turcan, Abdel-Wahab, Edwards, Khanin, Figueroa, Melnick, Wellen, ORourke, Berger, Chan, Levine, Mellinghoff, Thompson: "IDH mutation impairs histone demethylation and results in a block to cell differentiation." in: Nature, Vol. 483, Issue 7390, pp. 474-8, (2012) (PubMed).

  • 抗原

    KDM4C (Lysine (K)-Specific Demethylase 4C (KDM4C))

    别名

    JMJD2C

    背景

    JMJD2C is a member of the Jumonji domain 2 (JMJD2) family. It contains one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma.
    Alias Symbols: FLJ25949, GASC1, JHDM3C, JMJD2C, KIAA0780, bA146B14.1
    Protein Interaction Partner: UBC, HIST2H3C, HDAC3, PPARG, HDAC1, H3F3A, HIST1H3A, KDM4C, KDM4A,
    Protein Size: 813

    分子量

    92 kDa

    基因ID

    23081

    NCBI登录号

    NM_001146695, NP_001140167

    UniProt

    F5H347

    途径

    Nuclear Hormone Receptor Binding, Warburg Effect
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