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DMAP1 抗体 (N-Term)

This 兔 多克隆 anti-DMAP1 antibody specifically detects DMAP1 in WB. The antibody is reactive with 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 斑马鱼 和 马 samples.
产品编号 ABIN2777663
发货至: 中国
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Quick Overview for DMAP1 抗体 (N-Term) (ABIN2777663)

抗原

See all DMAP1 抗体
DMAP1 (DNA Methyltransferase 1-Associated Protein 1 (DMAP1))

适用

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人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 斑马鱼, 马

宿主

  • 41
  • 4
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克隆类型

  • 33
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多克隆

标记

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This DMAP1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    DAWTKAETDH LFDLSRRFDL RFVVIHDRYD HQQFKKRSVE DLKERYYHIC

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

    产品特性

    This is a rabbit polyclonal antibody against DMAP1. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human DMAP1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 467 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    DMAP1 (DNA Methyltransferase 1-Associated Protein 1 (DMAP1))

    别名

    DMAP1

    背景

    DMAP1 is a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described.
    Alias Symbols: EAF2, SWC4, MEAF2, DNMAP1, DNMTAP1
    Protein Interaction Partner: SOX2, UBC, RNF2, HECW2, RUVBL2, SRCAP, CFDP1, RUVBL1, DENR, VPS72, TOMM34, TSG101, H2AFZ, DAXX, SMARCAD1, SUMO2, EPC1, ACTL6A, ACTA1, PPP2R2D, ING3, MORF4L1, BRD8, KAT5, TRRAP, YEATS4, EP400, EPC2, MYC, MAX, ACTG1, ACTB, MRGBP, MORF4L2, MNAT1, HDAC1, tat,
    Protein Size: 467

    分子量

    51 kDa

    基因ID

    55929

    NCBI登录号

    NM_001034024, NP_001029196

    UniProt

    Q9NPF5
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