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SNF8 抗体 (N-Term)

This anti-SNF8 antibody is a 兔 多克隆 antibody detecting SNF8 in WB 和 IHC. Suitable for 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼 和 山羊.
产品编号 ABIN2777633
发货至: 中国

Quick Overview for SNF8 抗体 (N-Term) (ABIN2777633)

抗原

See all SNF8 抗体
SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))

适用

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人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, 山羊

宿主

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克隆类型

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多克隆

标记

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This SNF8 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    N-Term

    序列

    GTVLAEDQLA QMSKQLDMFK TNLEEFASKH KQEIRKNPEF RVQFQDMCAT

    预测反应

    Cow: 100%, Dog: 100%, Goat: 79%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against Snf8. It was validated on Western Blot.

    纯化方法

    Affinity Purified
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 258 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))

    别名

    Snf8

    背景

    Snf8 is required for degradation of both endocytosed EGF and EGFR, but not for the EGFR ligand-mediated internalization. It is a component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. The ESCRT-II complex may also play a role in transcription regulation by participating in derepression of transcription by RNA polymerase II, possibly via its interaction with ELL.
    Alias Symbols: D11moh34, MGC105799, RGD1310144
    Protein Size: 258

    分子量

    28 kDa

    基因ID

    287645

    NCBI登录号

    NM_001007804, NP_001007805

    UniProt

    Q5RK19
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