DUSP12 抗体 (N-Term)
Quick Overview for DUSP12 抗体 (N-Term) (ABIN2777632)
抗原
See all DUSP12 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- VEDLWRLFVP ALDKPETDLL SHLDRCVAFI GQARAEGRAV LVHCHAGVSR
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预测反应
- Cow: 100%, Dog: 86%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against DUSP12. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human DUSP12
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anti-Dual Specificity Phosphatase 12 (DUSP12) (AA 1-340) antibody
DUSP12 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 12 (DUSP12) (AA 1-340) antibodyDUSP12 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 12 (DUSP12) antibodyDUSP12 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 12 (DUSP12) antibodyDUSP12 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 12 (DUSP12) (AA 231-340) antibodyDUSP12 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 12 (DUSP12) antibodyDUSP12 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 12 (DUSP12) (AA 72-121) antibodyDUSP12 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, Pig, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 12 (DUSP12) (AA 130-270) antibodyDUSP12 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 12 (DUSP12) (N-Term) antibodyDUSP12 适用: 人, 小鼠, 大鼠, Cow WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 340 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- DUSP12 (Dual Specificity Phosphatase 12 (DUSP12))
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别名
- DUSP12
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背景
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DUSP12 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. DUSP12 is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain.The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain.
Alias Symbols: DUSP1, YVH1
Protein Interaction Partner: PPP2R3B, HSPB8, RABAC1, CALCOCO2, USO1, EIF5, CCNH, UBC, APP, NR1H2, KIAA1377, MBD6, PTN,
Protein Size: 340 -
分子量
- 38 kDa
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基因ID
- 11266
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NCBI登录号
- NM_007240, NP_009171
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UniProt
- Q9UNI6
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途径
- Regulation of Carbohydrate Metabolic Process
抗原
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