PIAS3 抗体 (Middle Region)
Quick Overview for PIAS3 抗体 (Middle Region) (ABIN2777575)
抗原
See all PIAS3 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Middle Region
-
序列
- DEIQFMEDGS WCPMKPKKEA SEVCPPPGYG LDGLQYSPVQ GGDPSENKKK
-
预测反应
- Cow: 79%, Dog: 86%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Rabbit: 79%, Rat: 79%
-
产品特性
- This is a rabbit polyclonal antibody against PIAS3. It was validated on Western Blot using a cell lysate as a positive control.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human PIAS3
-
-
anti-Protein Inhibitor of Activated STAT, 3 (PIAS3) (N-Term) antibody
PIAS3 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Inhibitor of Activated STAT, 3 (PIAS3) (AA 453-550) antibodyPIAS3 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 4F12 unconjugated
anti-Protein Inhibitor of Activated STAT, 3 (PIAS3) (AA 452-628) antibodyPIAS3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Inhibitor of Activated STAT, 3 (PIAS3) (N-Term) antibodyPIAS3 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein Inhibitor of Activated STAT, 3 (PIAS3) (AA 399-628) antibodyPIAS3 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein Inhibitor of Activated STAT, 3 (PIAS3) (N-Term) antibodyPIAS3 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein Inhibitor of Activated STAT, 3 (PIAS3) (AA 548-597) antibodyPIAS3 适用: 人, 大鼠, 犬, Cow, Pig, 马, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein Inhibitor of Activated STAT, 3 (PIAS3) (AA 95-126), (N-Term) antibodyPIAS3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB0671 unconjugated
anti-Protein Inhibitor of Activated STAT, 3 (PIAS3) (AA 588-619) antibodyPIAS3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB0673 unconjugated
anti-Protein Inhibitor of Activated STAT, 3 (PIAS3) (C-Term) antibodyPIAS3 适用: 人, 大鼠, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
-
说明
-
Antigen size: 628 AA
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- PIAS3 (Protein Inhibitor of Activated STAT, 3 (PIAS3))
-
别名
- PIAS3
-
背景
-
PIAS3 is a member of the protein inhibitor of activated STAT (PIAS) family. It also activates TGF-beta/SMAD transcriptional responses. This gene encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. The protein functions as a SUMO (small ubiquitin-like modifier)-E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity. Alternatively spliced transcript variants of this gene have been identified, but the full-length nature of some of these variants has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FLJ14651, ZMIZ5
Protein Interaction Partner: UBC, HIC1, TRIM63, TRIM55, TAB2, SUMO1, CBS, SUMO2, SUMO3, STAT3, NCOA2, CREM, PRPF40A, SERPINA10, GEMIN4, UBE2I, SKIL, HNRNPK, ZFHX3, SERBP1, SATB1, ERBB4, Bcl11a, ELAVL1, PPP1CA, Grm7, Grm8, Grm6, Grm4, TRIM8, RAC1, C19orf60, CARHSP1, UBA1, PSMC1, TRIM2
Protein Size: 628 -
分子量
- 68 kDa
-
基因ID
- 10401
-
NCBI登录号
- NM_006099, NP_006090
-
UniProt
- Q9Y6X2
-
途径
- JAK/STAT Signaling
抗原
-
