T-Box 22 抗体 (Middle Region)
Quick Overview for T-Box 22 抗体 (Middle Region) (ABIN2777562)
抗原
See all T-Box 22 (TBX22) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- QSMHKYKPRV HVIEQGSSVD LSQIQSLPTE GVKTFSFKET EFTTVTAYQN
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预测反应
- Cow: 86%, Horse: 86%, Human: 100%, Mouse: 79%, Pig: 86%, Rabbit: 79%, Rat: 86%
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产品特性
- This is a rabbit polyclonal antibody against TBX22. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human TBX22
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 520 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "TBX22 mutations are a frequent cause of non-syndromic cleft palate in the Thai population." in: Clinical genetics, Vol. 72, Issue 5, pp. 478-83, (2007) (PubMed).
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: "TBX22 mutations are a frequent cause of non-syndromic cleft palate in the Thai population." in: Clinical genetics, Vol. 72, Issue 5, pp. 478-83, (2007) (PubMed).
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- T-Box 22 (TBX22)
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别名
- TBX22
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背景
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This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene have been associated with the inherited X-linked disorder, Cleft palate with ankyloglossia, and it is believed to play a major role in human palatogenesis.This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene have been associated with the inherited X-linked disorder, Cleft palate with ankyloglossia, and it is believed to play a major role in human palatogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CLPA, TBXX, dJ795G23.1, CPX
Protein Interaction Partner: VENTX, HSP90AA1, APP,
Protein Size: 520 -
分子量
- 58 kDa
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基因ID
- 50945
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NCBI登录号
- NM_016954, NP_058650
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UniProt
- Q9Y458
抗原
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