PAX6 抗体 (N-Term)
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北京 101111
Quick Overview for PAX6 抗体 (N-Term) (ABIN2777559)
抗原
See all PAX6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- GRPLPDSTRQ KIVELAHSGA RPCDISRILQ THADAKVQVL DNQNVSNGCV
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against PAX6. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human PAX6
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 436 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PAX6 (Paired Box 6 (PAX6))
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别名
- PAX6
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背景
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PAX6 is one of many human homologues of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA,This gene encodes paired box gene 6, one of many human homologues of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA, and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause aniridia as well as Peter's anomaly, both ocular diseases.
Alias Symbols: AN, AN2, D11S812E, MGC17209, MGDA, WAGR
Protein Interaction Partner: IPO13, Dlg4, NKIRAS2, Cacnb3, Pax6, Diap1, SMAD5, SMAD4, SMAD3, SMAD1, AR, HIPK2, SUMO1, SMARCA4, TP73, SHANK3, PBX1, VSX2, EN1, TRIM11, HOMER3, SIX3, INADL, EP300, SOX10, RGS3, DIAPH1, MAFG, RAX, DYNLL1, DLG1, CDX2, TBP, SOX3, MITF, HOXB1, SOX2, LHX2, TA
Protein Size: 436 -
分子量
- 48 kDa
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基因ID
- 5080
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NCBI登录号
- NM_001604, NP_001595
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途径
- Peptide Hormone Metabolism, Carbohydrate Homeostasis
抗原
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