MAP4K6 抗体 (Middle Region)
Quick Overview for MAP4K6 抗体 (Middle Region) (ABIN2777554)
抗原
See all MAP4K6 (MINK1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Middle Region
-
序列
- PDSSPVLSPG NKAKPDDHRS RPGRPADFVL LKERTLDEAP RPPKKAMDYS
-
预测反应
- Cow: 85%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
-
产品特性
- This is a rabbit polyclonal antibody against MINK1. It was validated on Western Blot using a cell lysate as a positive control.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human MINK1
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
-
说明
-
Antigen size: 1312 AA
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- MAP4K6 (MINK1) (Misshapen-Like Kinase 1 (MINK1))
-
别名
- MINK1
-
背景
-
MINK1 is a serine/threonine kinase belonging to the germinal center kinase (GCK) family. The protein is structurally similar to the kinases that are related to NIK and may belong to a distinct subfamily of NIK-related kinases within the GCK family. Studies of the mouse homolog indicate an up-regulation of expression in the course of postnatal mouse cerebral development and activation of the cJun N-terminal kinase (JNK) and the p38 pathways.This gene encodes a serine/threonine kinase belonging to the germinal center kinase (GCK) family. The protein is structurally similar to the kinases that are related to NIK and may belong to a distinct subfamily of NIK-related kinases within the GCK family. Studies of the mouse homolog indicate an up-regulation of expression in the course of postnatal mouse cerebral development and activation of the cJun N-terminal kinase (JNK) and the p38 pathways. Alternative splicing occurs at this locus and four transcript variants encoding distinct isoforms have been identified.
Alias Symbols: B55, MAP4K6, MGC21111, MINK, YSK2, ZC3, hMINK, hMINKbeta
Protein Interaction Partner: UBC, HSP90AA1, NEDD4L, CASKIN1, SPTBN2, PKP4, ABI1, TUBA1B, KIFAP3, YWHAB, YWHAZ, NCK1, NEFM, MAP1B, CALM3, ACTA2,
Protein Size: 1312 -
分子量
- 148 kDa
-
基因ID
- 50488
-
NCBI登录号
- NM_001024937, NP_001020108
-
UniProt
- Q5U8Z0
-
途径
- Synaptic Membrane
抗原
-