NKX6-1 抗体 (N-Term)
Quick Overview for NKX6-1 抗体 (N-Term) (ABIN2777547)
抗原
See all NKX6-1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- MLAVGAMEGT RQSAFLLSSP PLAALHSMAE MKTPLYPAAY PPLPAGPPSS
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预测反应
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
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产品特性
- This is a rabbit polyclonal antibody against NKX6-1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human NKX6-1
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anti-NK6 Homeobox 1 (NKX6-1) antibody
NKX6-1 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal NKX61-2561 unconjugated
anti-NK6 Homeobox 1 (NKX6-1) (AA 1-367) antibodyNKX6-1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-NK6 Homeobox 1 (NKX6-1) (Internal Region) antibodyNKX6-1 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-NK6 Homeobox 1 (NKX6-1) (AA 191-275) antibodyNKX6-1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1B7 unconjugated
anti-NK6 Homeobox 1 (NKX6-1) antibodyNKX6-1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-NK6 Homeobox 1 (NKX6-1) (AA 285-314) antibodyNKX6-1 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-NK6 Homeobox 1 (NKX6-1) (N-Term) antibodyNKX6-1 适用: 人, 小鼠, 大鼠, 犬, 马, Pig, 兔, Cow, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-NK6 Homeobox 1 (NKX6-1) (AA 284-312) antibodyNKX6-1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-NK6 Homeobox 1 (NKX6-1) (AA 284-314), (C-Term) antibodyNKX6-1 适用: 人, 小鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 367 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- NKX6-1 (NK6 Homeobox 1 (NKX6-1))
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别名
- NKX6-1
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背景
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NKX6-1 is the transcription factor which binds to specific A/T-rich DNA sequences in the promoter regions of a number of genes. NKX6-1 is involved in transcriptional regulation in islet beta cells. Binds to the insulin promoter and is involved in regulation of the insulin gene. Together with NKX2-2 and IRX3, NKX6-1 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. NKX6-1 belongs to the class II proteins of neuronal progenitor factors, which are induced by SHH signals.In the pancreas, NKX6.1 is required for the development of beta cells and is a potent bifunctional transcription regulator that binds to AT-rich sequences within the promoter region of target genes Iype et al. (2004) [PubMed 15056733].[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-300 U66797.1 1-300 301-307 AC096766.3 119394-119400 c 308-676 U66797.1 308-676 677-849 U66798.1 7-179 850-1116 U66799.1 7-273
Alias Symbols: NKX6.1, NKX6A
Protein Size: 367 -
分子量
- 38 kDa
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基因ID
- 4825
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NCBI登录号
- NM_006168, NP_006159
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UniProt
- P78426
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途径
- Dopaminergic Neurogenesis, Positive Regulation of Peptide Hormone Secretion
抗原
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