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GATA2 抗体 (N-Term)

Name: GATA2 抗体 (N-Term)
SKU: ABIN2777458
Availability: OutOfStock

This anti-GATA2 antibody is a 兔多克隆 antibody detecting GATA2 in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马和兔. This Primary Antibody has been cited in 6+ publications.

Host: Rabbit Target Name: GATA2 Sample Tissue: Human HepG2 Whole Cell Antibody Dilution: 1ug/ml (GATA2 抗体 (N-Term))

IHC

Lanes : Lane 1: 30ug mouse liver lysateLane 2: 30ug mouse N2a cell lysate Primary Antibody Dilution : 1:500 Secondary Antibody : Anti-rabbit-HRP Secondary Antibody Dilution : 1:2500 Gene Name : GATA2 Submitted by : A Kalyani and Vinayak Gupta IIT Madras (GATA2 抗体 (N-Term))

WB Suggested Anti-GATA2 antibody Titration: 1 ug/mL Sample Type: Human K562 (GATA2 抗体 (N-Term))

WB Suggested Anti-GATA2 Antibody Titration: 1. (GATA2 抗体 (N-Term))

5 images

(6 references)

产品编号 ABIN2777458

发货至: 中国

Quick Overview for GATA2 抗体 (N-Term) (ABIN2777458)

抗原

See all GATA2 抗体

GATA2 (GATA Binding Protein 2 (GATA2))

适用

人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔

宿主

兔

克隆类型

多克隆

标记

This GATA2 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC)

Discover our top product GATA2 Primary Antibody

抗原表位
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N-Term

序列

PYYANPAHAR ARVSYSPAHA RLTGGQMCRP HLLHSPGLPW LDGGKAALSA

预测反应

Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

产品特性

This is a rabbit polyclonal antibody against GATA2. It was validated on Western Blot and immunohistochemistry.

纯化方法

Protein A purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human GATA2
anti-GATA Binding Protein 2 (GATA2) (AA 1-102) antibody
GATA2 适用: 人 WB, ELISA, IF, RNAi 宿主: 小鼠 Monoclonal 2D11 unconjugated

anti-GATA Binding Protein 2 (GATA2) (AA 1-102) antibody
GATA2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2F12 unconjugated

anti-GATA Binding Protein 2 (GATA2) (AA 1-102) antibody
GATA2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1A5 unconjugated

anti-GATA Binding Protein 2 (GATA2) (AA 380-407) antibody
GATA2 适用: 人 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated

anti-GATA Binding Protein 2 (GATA2) (AA 175-480) antibody
GATA2 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-GATA Binding Protein 2 (GATA2) (AA 1-300) antibody
GATA2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-GATA Binding Protein 2 (GATA2) (AA 1-480) antibody
GATA2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-GATA Binding Protein 2 (GATA2) antibody
GATA2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-GATA Binding Protein 2 (GATA2) (AA 117-338) antibody
GATA2 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-GATA Binding Protein 2 (GATA2) antibody
GATA2 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 480 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Wang, Zhu, Guo, Dong, Liu, Yin, Zhang, Li, Liu, Ma, Song, He, Wang, Wang, Zhang, Li, Yu: "A regulatory circuit comprising GATA1/2 switch and microRNA-27a/24 promotes erythropoiesis." in: Nucleic acids research, Vol. 42, Issue 1, pp. 442-57, (2013) (PubMed).

Fujiwara, Yokoyama, Okitsu, Kamata, Fukuhara, Onishi, Fujimaki, Takahashi, Ishizawa, Bresnick, Harigae: "Gene expression profiling identifies HOXB4 as a direct downstream target of GATA-2 in human CD34+ hematopoietic cells." in: PLoS ONE, Vol. 7, Issue 9, pp. e40959, (2012) (PubMed).

Jack, Crossley: "GATA proteins work together with friend of GATA (FOG) and C-terminal binding protein (CTBP) co-regulators to control adipogenesis." in: The Journal of biological chemistry, Vol. 285, Issue 42, pp. 32405-14, (2010) (PubMed).

Huang, Niu, Liu, Wang, Sturgis, Wei: "The functional IGFBP7 promoter -418G>A polymorphism and risk of head and neck cancer." in: Mutation research, Vol. 702, Issue 1, pp. 32-9, (2010) (PubMed).

Mammoto, Connor, Mammoto, Yung, Huh, Aderman, Mostoslavsky, Smith, Ingber: "A mechanosensitive transcriptional mechanism that controls angiogenesis." in: Nature, Vol. 457, Issue 7233, pp. 1103-8, (2009) (PubMed).

Tsuzuki, Kitajima, Nakano, Glasow, Zelent, Enver: "Cross talk between retinoic acid signaling and transcription factor GATA-2." in: Molecular and cellular biology, Vol. 24, Issue 15, pp. 6824-36, (2004) (PubMed).
抗原

GATA2 (GATA Binding Protein 2 (GATA2))

别名

GATA2

背景

The GATA family of transcription factors, which contain zinc fingers in their DNA binding domain, have emerged as candidate regulators of gene expression in hematopoietic cells is essential for normal primitive and definitive erythropoiesis and is expressed at high levels in erythroid cells, mast cells, and megakaryocytes. GATA2 is expressed in hematopoietic progenitors, including early erythroid cells, mast cells, and megakaryocytes, and also in nonhematopoietic embryonic stem cells.
Alias Symbols: DCML, NFE1B, MONOMAC
Protein Interaction Partner: NOTCH2NL, KRTAP10-3, KRTAP10-9, KRT40, PRR20A, ADAMTSL4, TRAF1, PSMA3, MDFI, GOLGA2, FHL3, TRIM23, AKT1, BMI1, SPI1, SMAD4, ELAVL1, KAT2A, EP300, MED1, POU1F1, POU2AF1, ZBTB32, ZFPM1, ZBTB16, HDAC5, HDAC3, HHEX, RARA, RXRA, MAPK1, JUN, CEBPA, STAT3, PML,
Protein Size: 480

分子量

50 kDa

基因ID

2624

NCBI登录号

NM_032638, NP_116027

UniProt

P23769

途径

Stem Cell Maintenance