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SOX2 抗体 (N-Term)

Name: SOX2 抗体 (N-Term)
SKU: ABIN2777428
Availability: OutOfStock

Cited in 2+ publications. This 兔多克隆 anti-SOX2 antibody specifically detects SOX2 in WB 和 IHC. The antibody is reactive with 人, 小鼠, 大鼠, 山羊, Cow, Pig, 绵羊, 斑马鱼, 马, 兔和犬 samples.

Host: Mouse Target Name: SOX2 Sample Tissue: Mouse Pancreas Antibody Dilution: 1ug/ml (SOX2 抗体 (N-Term))

Immunohistochemistry (IHC) image for anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (N-Term) antibody (ABIN2777428) (SOX2 抗体 (N-Term))

IHC

Host: Rabbit Target Name: SOX2 Sample Tissue: Mouse Liver Antibody Dilution: 1ug/ml (SOX2 抗体 (N-Term))

IHC

WB Suggested Anti-SOX2 Antibody Titration: 0. (SOX2 抗体 (N-Term))

Researcher:Kim Perry, University of Illinois Application:IHC Species+tissue/cell type:Xenopus laevis cornea epithellium Primary antibody dilution:1:300 Secondary antibody:Goat anti-rabbit -rhodamine Secondary antibody dilution:1:300 (SOX2 抗体 (N-Term))

IHC

Host: Rabbit Target Name: SOX2 Sample Tissue: Human 293T Antibody Dilution: 1. (SOX2 抗体 (N-Term))

Sample Type: Lane 1: 20 ug U87 lysate Primary Antibody Dilution: 1:1000 Secondary Antibody: Anti-rabbit-HRP Secondary Antibody Dilution: 1:2000 Submitted by: Ander Matheu Fernandez, Biodonostia Institute (SOX2 抗体 (N-Term))

9 images

(2 references)

产品编号 ABIN2777428

发货至: 中国

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Quick Overview for SOX2 抗体 (N-Term) (ABIN2777428)

抗原

See all SOX2 抗体

SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

适用

人, 小鼠, 大鼠, 山羊, Cow, Pig, 绵羊, 斑马鱼, 马, 兔, 犬

宿主

兔

克隆类型

多克隆

标记

This SOX2 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC)

Discover our top product SOX2 Primary Antibody

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N-Term

序列

MYNMMETELK PPGPQQTSGG GGGNSTAAAA GGNQKNSPDR VKRPMNAFMV

预测反应

Cow: 100%, Dog: 100%, Goat: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 91%

产品特性

This is a rabbit polyclonal antibody against SOX2. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human SOX2
anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) antibody
KO Validated SOX2 适用: 人 WB, IF, FACS, ICC, IHC (p), IP, IHC (fro), CUT&RUN 宿主: 兔 Polyclonal unconjugated

anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 227-317) antibody
SOX2 适用: 人, 小鼠, 大鼠, 山羊 WB, ELISA, FACS, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 1-317) antibody
SOX2 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 176-305) antibody
SOX2 适用: 人, 小鼠 WB, IHC, ELISA, Coat, StM 宿主: 小鼠 Monoclonal SOX2-1791 unconjugated

anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) antibody
SOX2 适用: 人 IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 10F10 unconjugated

anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 89-119), (N-Term) antibody
SOX2 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB14026 unconjugated

anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (Middle Region) antibody
SOX2 适用: 人, 小鼠, 大鼠, 山羊, Cow, 绵羊, 斑马鱼, 马, 兔, 犬, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 89-119) antibody
SOX2 适用: 人 WB, IHC, ELISA, IF, FACS 宿主: 兔 Polyclonal unconjugated

anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 251-284) antibody
SOX2 适用: 人 WB, IF, FACS 宿主: 兔 Polyclonal RB14259 unconjugated

anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (N-Term) antibody
Verified SOX2 适用: 人 WB, IHC, ELISA, FACS 宿主: 山羊 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 317 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Lenz, Konecna, Tichy, Machacova, Fiala, Hurnik, Kyllar: "Unique expression patterns of the embryonal stem cell marker SOX2 and hormone receptors suggest the existence of a subpopulation of epithelial stem/progenitor cells in porcine and bovine endometrium." in: Veterinary medicine and science, (2022) (PubMed).

Perry, Thomas, Henry: "Expression of pluripotency factors in larval epithelia of the frog Xenopus: evidence for the presence of cornea epithelial stem cells." in: Developmental biology, Vol. 374, Issue 2, pp. 281-94, (2013) (PubMed).
抗原

SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

别名

SOX2

背景

SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in this gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation. This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ANOP3, MCOPS3, MGC2413
Protein Interaction Partner: SUMO1, DMAP1, TBX2, SETD7, FAM21A, FZR1, MMS19, MRPS35, ZNF462, LSM2, CCAR2, MIER1, ZDBF2, CHD8, EP400, TSHZ3, RANBP10, ZNF687, XPO5, INTS2, MTA3, CORO1B, CASC5, MRPS22, KCMF1, MEPCE, TRERF1, INTS9, PARVA, SCYL2, CHD7, ZCCHC8, SOX6, BRIX1, SAMD4B, GID8, C
Protein Size: 317

分子量

34 kDa

基因ID

6657

NCBI登录号

NM_003106, NP_003097

UniProt

P48431

途径

Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis