SCMH1 抗体 (Middle Region)
Quick Overview for SCMH1 抗体 (Middle Region) (ABIN2777417)
抗原
See all SCMH1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- LTGDNLQPPG TKVVIPKNPY PASDVNTEKP SIHSSTKTVL EHQPGQRGRK
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预测反应
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 86%, Yeast: 79%
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产品特性
- This is a rabbit polyclonal antibody against SCMH1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human SCMH1
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 591 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SCMH1 (Sex Comb On Midleg Homolog 1 (SCMH1))
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别名
- SCMH1
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背景
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SCMH1 is a component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
Alias Symbols: Scml3
Protein Interaction Partner: UBQLN1, RNF2, MAGEA12, BMI1, UBQLN4, PHC3, CBX4, PCGF2, PHC2, PHC1, MAML3, LZTR1, PCBD1, EWSR1, TMEM11, SCMH1, MOB4, TOB1, POLR2M, LYPLA2, GMNN, HK1, Cbx2,
Protein Size: 591 -
分子量
- 65 kDa
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基因ID
- 22955
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NCBI登录号
- NM_012236, NP_036368
抗原
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