KLF8 抗体 (N-Term)
Quick Overview for KLF8 抗体 (N-Term) (ABIN2777342)
抗原
See all KLF8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- LSFHKPKAPL QPASMLQAPI RPPKPQSSPQ TLVVSTSTSD MSTSANIPTV
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预测反应
- Cow: 79%, Dog: 79%, Horse: 77%, Human: 100%, Rabbit: 86%
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产品特性
- This is a rabbit polyclonal antibody against KLF8. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human KLF8
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 359 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "KLF8 promotes tumorigenesis, invasion and metastasis of colorectal cancer cells by transcriptional activation of FHL2." in: Oncotarget, Vol. 6, Issue 28, pp. 25402-17, (2015) (PubMed).
: "Krüppel?like factor expression and correlation with FAK, MMP?9 and E?cadherin expression in hepatocellular carcinoma." in: Molecular medicine reports, Vol. 8, Issue 1, pp. 81-8, (2013) (PubMed).
: "Small interference RNA targeting Krüppel-like factor 8 inhibits the renal carcinoma 786-0 cells growth in vitro and in vivo." in: Journal of cancer research and clinical oncology, Vol. 136, Issue 8, pp. 1255-65, (2010) (PubMed).
: "Up-regulation of Krüppel-like factor 8 promotes tumor invasion and indicates poor prognosis for hepatocellular carcinoma." in: Gastroenterology, Vol. 139, Issue 6, pp. 2146-2157.e12, (2010) (PubMed).
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: "KLF8 promotes tumorigenesis, invasion and metastasis of colorectal cancer cells by transcriptional activation of FHL2." in: Oncotarget, Vol. 6, Issue 28, pp. 25402-17, (2015) (PubMed).
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- KLF8 (Kruppel-Like Factor 8 (KLF8))
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别名
- KLF8
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背景
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KLF8 is abnormally expressed in female patients with X autosome translocation t(X,21)(p11.2,q22.3) and non-syndromic mental retardation.
Alias Symbols: BKLF3, DKFZp686O08126, DXS741, MGC138314, ZNF741
Protein Interaction Partner: Dlg4, APP, UBC, XPO1, PARP1, KAT2B, EP300, CREBBP, FHL3, CTBP2,
Protein Size: 359 -
分子量
- 39 kDa
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基因ID
- 11279
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NCBI登录号
- NM_007250, NP_009181
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UniProt
- O95600
抗原
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